L-Phenylalanine, 4-(methoxycarbonyl)- (9CI)

Base Information

Chemical Name:L-Phenylalanine, 4-(methoxycarbonyl)- (9CI)
CAS No.:473259-95-9
Molecular Formula:C11H13NO4
Molecular Weight:223.229
Hs Code.:
Mol file:473259-95-9.mol

Synonyms:L-Phenylalanine, 4-(methoxycarbonyl)- (9CI);L-Phenylalanine, 4-(methoxycarbonyl)-

Suppliers and Price of L-Phenylalanine, 4-(methoxycarbonyl)- (9CI)

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of L-Phenylalanine, 4-(methoxycarbonyl)- (9CI)

Chemical Property:

Melting Point:220 °C
PSA：89.62000
LogP:1.12790

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of L-Phenylalanine, 4-(methoxycarbonyl)- (9CI)

There total 6 articles about L-Phenylalanine, 4-(methoxycarbonyl)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: C₂₀H₂₉NO₆

: 473259-95-9,151872-17-2
(S)-2-amino-3-(4-(methoxycarbonyl)phenyl)propanoic acid

Guidance literature:: With methoxybenzene; trifluoroacetic acid; In dichloromethane; at 20 ℃; for 18h;
DOI:10.1021/acs.jmedchem.8b01007

Reference yield:

: 340732-80-1
Boc-cmF(OMe)-OtBu

: 473259-95-9,151872-17-2
(S)-2-amino-3-(4-(methoxycarbonyl)phenyl)propanoic acid

Guidance literature:: With trifluoroacetic acid; In dichloromethane;

Reference yield:

: 5513-40-6
benzyl N-carbobenzyloxy-L-tyrosine

: 473259-95-9,151872-17-2
(S)-2-amino-3-(4-(methoxycarbonyl)phenyl)propanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 75 percent / 2,6-lutidine / CH₂Cl₂ / -40 °C

2: Et₃N, 1,1'-bis(diphenylphosphino)ferrocene / Pd(OAc)2 / dimethylformamide / 60 °C

3: H₂ / Pd/C

With 2,6-dimethylpyridine; 1,1'-bis-(diphenylphosphino)ferrocene; hydrogen; triethylamine; palladium diacetate; palladium on activated charcoal; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(96)01490-6