N-Benzyloxycarbonyl-L-tyrosine

Base Information

Chemical Name:N-Benzyloxycarbonyl-L-tyrosine
CAS No.:1164-16-5
Molecular Formula:C17H17NO5
Molecular Weight:315.326
Hs Code.:29242990
European Community (EC) Number:214-609-6
DSSTox Substance ID:DTXSID301313627
Nikkaji Number:J80.060K
Wikidata:Q106902935
ChEMBL ID:CHEMBL291833
Mol file:1164-16-5.mol

Synonyms:N-benzyloxycarbonyl-l-tyrosine;N-cbz-l-Tyr

Suppliers and Price of N-Benzyloxycarbonyl-L-tyrosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Acrotein
Cbz-L-tyrosine 97%
25g
$ 45.28

Acrotein
Cbz-L-tyrosine 97%
100g
$ 114.58

Activate Scientific
Cbz-L-tyrosine 95% ee
100 g
$ 132.00

Activate Scientific
Cbz-L-tyrosine 95% ee
25 g
$ 44.00

Activate Scientific
Cbz-L-tyrosine 95% ee
5 g
$ 16.00

Activate Scientific
Cbz-L-tyrosine 95% ee
250 g
$ 256.00

AK Scientific
N-Benzyloxycarbonyl-L-tyrosine
100g
$ 105.00

Alfa Aesar
N-Benzyloxycarbonyl-L-tyrosine, 99%, may contain up to ca 10% water
25g
$ 89.20

Alfa Aesar
N-Benzyloxycarbonyl-L-tyrosine, 99%, may contain up to ca 10% water
5g
$ 31.00

Ambeed
Z-Tyr-OH 95%
25g
$ 21.00

Total 110 raw suppliers

Chemical Property of N-Benzyloxycarbonyl-L-tyrosine

Chemical Property:

Appearance/Colour:White to off-white crystalline powder
Vapor Pressure:7.21E-14mmHg at 25°C
Melting Point:57-60 °C(lit.)
Refractive Index:10.0 ° (C=1, AcOH)
Boiling Point:570.8 °C at 760 mmHg
PKA:2.97±0.10(Predicted)
Flash Point:299 °C
PSA：95.86000
Density:1.323 g/cm³
LogP:2.70520
Storage Temp.:−20°C
Solubility.:Acetic Acid (Sparingly), DMSO (Slightly), Methanol (Sparingly)
Water Solubility.:1.53g/L(25 oC)
XLogP3:1.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:315.11067264
Heavy Atom Count:23
Complexity:386

Purity/Quality:

99% ^*data from raw suppliers

Cbz-L-tyrosine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi,Xn
Hazard Codes:Xi,Xn
Statements: 20/21/22-36/37/38
Safety Statements: 22-24/25-36-26-45-36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC(=O)NC(CC2=CC=C(C=C2)O)C(=O)O
Isomeric SMILES:C1=CC=C(C=C1)COC(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)O
Uses N-Cbz-L-tyrosine is an N-Cbz-protected form of L-Tyrosine (T899975). L-Tyrosine is an essential amino acid that exhibits in vitro antioxidant and antiradical activities. L-Tyrosine is used as a precursor to synthesize catecholamines (e.g. Norepinephrine HCl [N674500]) in human keratinocytes, and also for the synthesis of proteins and thyroid hormones.

Technology Process of N-Benzyloxycarbonyl-L-tyrosine

There total 36 articles about N-Benzyloxycarbonyl-L-tyrosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 60-18-4,18875-48-4,25619-78-7,30704-25-7
L-tyrosine

: 501-53-1,94274-21-2
benzyl chloroformate

: 1164-16-5
Z-L-Tyr-OH

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 4h; Inert atmosphere; Cooling with ice;
DOI:10.1021/ol4031155

Reference yield: 100.0%

: 5545-54-0
N-(benzyloxycarbonyl)-O-(1,1-dimethylethyl)-L-tyrosine

: 1164-16-5
Z-L-Tyr-OH

Guidance literature:: With triethylsilane; trifluoroacetic acid; In dichloromethane; for 0.583333h; Ambient temperature;
DOI:10.1016/S0040-4039(00)79116-7