ETHYL 1-(4-FLUOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBOXYLATE

Base Information

Chemical Name:ETHYL 1-(4-FLUOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBOXYLATE
CAS No.:288252-73-3
Molecular Formula:C₁₃H₁₃FN₂O₂
Molecular Weight:248.257
Hs Code.:2933199090
Mol file:288252-73-3.mol

Synonyms:RARECHEM AL BI 1356;SALOR-INT L317543-1EA;ETHYL 1-(4-FLUOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBOXYLATE;BUTTPARK 147\18-44

Suppliers and Price of ETHYL 1-(4-FLUOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBOXYLATE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Ethyl1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxylate 95+%
1g
$ 452.00

American Custom Chemicals Corporation
ETHYL 1-(4-FLUOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBOXYLATE 95.00%
100MG
$ 187.95

American Custom Chemicals Corporation
ETHYL 1-(4-FLUOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBOXYLATE 95.00%
10G
$ 7882.88

American Custom Chemicals Corporation
ETHYL 1-(4-FLUOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBOXYLATE 95.00%
5G
$ 4244.63

American Custom Chemicals Corporation
ETHYL 1-(4-FLUOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBOXYLATE 95.00%
1G
$ 1030.84

AK Scientific
Ethyl1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxylate
250mg
$ 224.00

Total 7 raw suppliers

Chemical Property of ETHYL 1-(4-FLUOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBOXYLATE

Chemical Property:

PSA：44.12000
LogP:2.49650

Purity/Quality:

95% ^*data from raw suppliers

Ethyl1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of ETHYL 1-(4-FLUOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBOXYLATE

There total 1 articles about ETHYL 1-(4-FLUOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 371-14-2
4-fluorophenylhydrazine

: 3788-94-1
2-ethoxymethylene-3-oxobutanoic acid ethyl ester

: 288252-73-3
ethyl 1-(4-fluorophenyl)-5-methylpyrazole-4-carboxylate

Guidance literature:: In ethanol; for 2h; Heating / reflux;

Reference yield:

: 288252-73-3
ethyl 1-(4-fluorophenyl)-5-methylpyrazole-4-carboxylate

: N-(1-(2-cyano-4-[1-(4-fluorophenyl)-5-methylpyrazole-4-carboxamide]phenyl-4-oxy))-4-oxobutyric acid

Guidance literature:: Multi-step reaction with 6 steps

1.1: sodium hydroxide / ethanol; water / 2 h / Heating / reflux

2.1: thionyl chloride / 1,2-dichloro-ethane / 0.5 h / 83 °C

3.1: pyridine / 1 h / 20 °C

4.1: sodium hydride / DMF (N,N-dimethyl-formamide) / 1 h / Cooling with ice

4.2: 2 h / 20 °C / Cooling with ice

5.1: tetrabutyl ammonium fluoride / tetrahydrofuran; acetonitrile / 1 h / 80 °C

6.1: toluene-4-sulfonic acid / nitrobenzene / 6 h / 110 °C

With sodium hydroxide; thionyl chloride; tetrabutyl ammonium fluoride; sodium hydride; toluene-4-sulfonic acid; In tetrahydrofuran; pyridine; DMF (N,N-dimethyl-formamide); ethanol; water; nitrobenzene; 1,2-dichloro-ethane; acetonitrile;