4,5,6,7-Tetrahydrofuro[2,3-C]pyridine

Base Information

Chemical Name:4,5,6,7-Tetrahydrofuro[2,3-C]pyridine
CAS No.:721927-08-8
Molecular Formula:C₇H₉NO
Molecular Weight:123.155
Hs Code.:
DSSTox Substance ID:DTXSID601288700
Mol file:721927-08-8.mol

Synonyms:4,5,6,7-TETRAHYDROFURO[2,3-C]PYRIDINE;721927-08-8;4H,5H,6H,7H-FURO[2,3-C]PYRIDINE;SCHEMBL13540;ZKAYEFAKZWTAGS-UHFFFAOYSA-N;DTXSID601288700;BCP26172;AKOS000161208;AB52640;CS-0513850;EN300-1076690

Suppliers and Price of 4,5,6,7-Tetrahydrofuro[2,3-C]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4,5,6,7-TETRAHYDROFURO-[2,3-C]-PYRIDINE 95.00%
5MG
$ 505.40

Total 1 raw suppliers

Chemical Property of 4,5,6,7-Tetrahydrofuro[2,3-C]pyridine

Chemical Property:

PSA：25.17000
LogP:1.25410
XLogP3:0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:123.068413911
Heavy Atom Count:9
Complexity:105

Purity/Quality:: 4,5,6,7-TETRAHYDROFURO-[2,3-C]-PYRIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCC2=C1C=CO2

Technology Process of 4,5,6,7-Tetrahydrofuro[2,3-C]pyridine

There total 5 articles about 4,5,6,7-Tetrahydrofuro[2,3-C]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 179060-28-7
6-(tert-butoxycarbonyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridine

: 721927-08-8
4,5,6,7-tetrahydrofuro[2,3-c]pyridine

Guidance literature:: With hydrogenchloride; In methanol; dichloromethane; at 20 ℃; for 2h;
DOI:10.1021/jm049884d

Reference yield:

: 498-60-2
furan-3-carboxaldehyde

: 721927-08-8
4,5,6,7-tetrahydrofuro[2,3-c]pyridine

Guidance literature:: Multi-step reaction with 5 steps

1: 55 percent / aq. NaOH / ethanol / 1 h / 0 °C

2: NaBH₄ / tetrahydrofuran / 2 h / 20 °C

3: 4.30 g / CH₂Cl₂ / 1 h

4: 45 percent / p-toluenesulfonic acid hydrate / toluene / 2 h / Heating

5: HCl / methanol; CH₂Cl₂ / 2 h / 20 °C

With hydrogenchloride; sodium hydroxide; sodium tetrahydroborate; toluene-4-sulfonic acid; In tetrahydrofuran; methanol; ethanol; dichloromethane; toluene;
DOI:10.1021/jm049884d

Reference yield:

: 53916-75-9
2-(furan-3-yl)ethylamine

: 721927-08-8
4,5,6,7-tetrahydrofuro[2,3-c]pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 4.30 g / CH₂Cl₂ / 1 h

2: 45 percent / p-toluenesulfonic acid hydrate / toluene / 2 h / Heating

3: HCl / methanol; CH₂Cl₂ / 2 h / 20 °C

With hydrogenchloride; toluene-4-sulfonic acid; In methanol; dichloromethane; toluene;
DOI:10.1021/jm049884d