Technology Process of (3-tert-butyl-1-(3-chlorophenyl)-1H-pyrazol-5-yl)methanamine
There total 17 articles about (3-tert-butyl-1-(3-chlorophenyl)-1H-pyrazol-5-yl)methanamine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: hydrogenchloride; sodium nitrite / water / 1 h / 0 - 5 °C
1.2: 1 h / 75 °C
2.1: sodium hydride / N,N-dimethyl-formamide / 0.25 h / 20 °C
2.2: 0.5 h / 20 - 100 °C
3.1: palladium 10% on activated carbon; hydrogen / methanol / 6 h / 20 °C
With
hydrogenchloride; palladium 10% on activated carbon; hydrogen; sodium hydride; sodium nitrite;
In
methanol; water; N,N-dimethyl-formamide;
- Guidance literature:
-
With
palladium 10% on activated carbon; hydrogen;
In
methanol;
at 20 ℃;
for 6h;
Reagent/catalyst;
Solvent;
Time;
Temperature;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: hydrazine hydrate / ethanol / 3 h / 20 °C / Reflux
2.1: hydrogenchloride; sodium nitrite / water / 1 h / 0 - 5 °C
2.2: 1 h / 75 °C
3.1: copper diacetate; pyridine / dichloromethane / 16 h / 20 °C
4.1: palladium 10% on activated carbon; hydrogen / methanol / 6 h / 20 °C
With
pyridine; hydrogenchloride; palladium 10% on activated carbon; hydrogen; copper diacetate; hydrazine hydrate; sodium nitrite;
In
methanol; ethanol; dichloromethane; water;
