4'-Hydroxymethyl-2,2':6',2''-terpyridine

Base Information

Chemical Name:4'-Hydroxymethyl-2,2':6',2''-terpyridine
CAS No.:148332-32-5
Molecular Formula:C₁₆H₁₃N₃O
Molecular Weight:263.29
Hs Code.:
DSSTox Substance ID:DTXSID701288696
Nikkaji Number:J2.111.729C
Mol file:148332-32-5.mol

Synonyms:148332-32-5;4'-Hydroxymethyl-2,2':6',2''-terpyridine;[2,2':6',2''-Terpyridine]-4'-methanol;[2,2':6',2''-Terpyridin]-4'-ylmethanol;(2,6-dipyridin-2-ylpyridin-4-yl)methanol;2,2':6',2''-Terpyridine-4'-methanol;SCHEMBL14263382;DTXSID701288696;2,2':6',2''-Terpyridin-4'-ylmethanol;CS-0371262;[2,2':6',2''-terpyridin]-4'-yl-methanol;E82748;J-400601;[6-(PYRIDIN-2-YL)-[2,2'-BIPYRIDIN]-4-YL]METHANOL

Suppliers and Price of 4'-Hydroxymethyl-2,2':6',2''-terpyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 13 raw suppliers

Chemical Property of 4'-Hydroxymethyl-2,2':6',2''-terpyridine

Chemical Property:

Boiling Point:462.2±40.0 °C(Predicted)
PKA:12.77±0.10(Predicted)
PSA：0.00000
Density:1.233±0.06 g/cm3(Predicted)
LogP:0.00000
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:263.105862047
Heavy Atom Count:20
Complexity:273

Purity/Quality:: 99.0% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=NC(=C1)C2=CC(=CC(=N2)C3=CC=CC=N3)CO

Technology Process of 4'-Hydroxymethyl-2,2':6',2''-terpyridine

There total 3 articles about 4'-Hydroxymethyl-2,2':6',2''-terpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 247058-06-6
2,2'-6',2''-terpyridine-4'-carboxylic acid methyl ester

: 148332-32-5
4'-(hydroxymethyl)-2,2';6',2''-terpyridineine

Guidance literature:: With sodium tetrahydroborate; lithium chloride; In ethanol; for 4h; Reflux;
DOI:10.1016/j.tetlet.2019.02.037

Reference yield: 85.0%

: 108295-45-0
4′-formyl-2,2′:6′2″-terpyridine

: 148332-32-5
4'-(hydroxymethyl)-2,2';6',2''-terpyridineine

Guidance literature:: With sodium tetrahydroborate; In tetrahydrofuran; at 0 ℃; for 0.25h;
DOI:10.1002/(sici)1099-0682(200004)2000:4<741::aid-ejic741>3.0.co;2-6

Reference yield:

: 148332-36-9
[2,2′:6′,2′′-terpyridine]-4′-carboxylic acid

: 148332-32-5
4'-(hydroxymethyl)-2,2';6',2''-terpyridineine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 20 °C

2: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 °C

With lithium aluminium tetrahydride; potassium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1002/cmdc.201700626