(R) Lisinopril

Base Information

Chemical Name:(R) Lisinopril
CAS No.:85955-59-5
Molecular Formula:C21H31N3O5
Molecular Weight:405.494
Hs Code.:
Mol file:85955-59-5.mol

Synonyms:N2-[(1R)-1-Carboxy-3-phenylpropyl)-L-lysyl]L-proline;(R) Lisinopril;(R)-1-[N2-(1-Carboxy-3-phenylpropyl)-L-lysyl]L-proline

Suppliers and Price of (R) Lisinopril

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
(R)Lisinopril
5 mg
$ 2800.00

American Custom Chemicals Corporation
(R)-LISINOPRIL 95.00%
10MG
$ 2728.69

American Custom Chemicals Corporation
(R)-LISINOPRIL 95.00%
1MG
$ 818.61

Total 12 raw suppliers

Chemical Property of (R) Lisinopril

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:666.441°C at 760 mmHg
PKA:2.18±0.10(Predicted)
Flash Point:356.851°C
PSA：132.96000
Density:1.252g/cm³
LogP:2.26430

Purity/Quality:

98%Min ^*data from raw suppliers

(R)Lisinopril ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses R,S,S-Isomer of Lisinopril (R)-Lisinopril is a R,S,S-isomer of (S)-Lisinopril (L469018), an orally active angiotensin-converting enzyme (ACE) inhibitor.

Technology Process of (R) Lisinopril

There total 6 articles about (R) Lisinopril which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 77726-95-5
(S)-1-[N₂-(1-carboxy-3-phenylpropyl]-L-lysyl]-L-proline

: 76547-98-3
Lisinopril

: 85955-59-5
lisinopril

Guidance literature:: With hydrogenchloride; In water; Resolution of racemate;

Reference yield:

: 103300-91-0
N^ε-(trifluoroacetyl)-N^α-<(S)-1-(ethoxycarbonyl)-3-phenylpropyl>-L-lysyl-L-proline

: 76547-98-3
Lisinopril

: 85955-59-5
lisinopril

Guidance literature:: With sodium hydroxide; sodium hydrogencarbonate; at 40 ℃; for 4h;
DOI:10.1021/jo00239a029

Reference yield:

: 710-11-2
2-oxo-4-phenylbutyric acid

: 4583-24-8
H-Lys(Boc)-Pro-OH

: 76547-98-3
Lisinopril

: 85955-59-5
lisinopril

Guidance literature:: With sodium hydroxide; Dowex 50 (H⁺, 50-100 mesh); sodium cyanoborohydride; Yield given. Multistep reaction. Yields of byproduct given; 1.) water, room temperature, pH 7.0;
DOI:10.1002/jps.2600740330