BIS(N-BOC)-2-DEOXYSTREPTAMINE

Base Information

Chemical Name:BIS(N-BOC)-2-DEOXYSTREPTAMINE
CAS No.:189157-45-7
Molecular Formula:C16H30N2O7
Molecular Weight:362.42
Hs Code.:
Mol file:189157-45-7.mol

Synonyms:BIS(N-BOC)-2-DEOXYSTREPTAMINE;BIS-BOC-2-DOS;TERT-BUTYL 4,5,6-TRIHYDROXYCYCLOHEXANE-1,3-DIYLDICARBAMATE

Suppliers and Price of BIS(N-BOC)-2-DEOXYSTREPTAMINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of BIS(N-BOC)-2-DEOXYSTREPTAMINE

Chemical Property:

Melting Point:212 - 213 °C (methanol)
PSA：137.35000
LogP:1.04120

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of BIS(N-BOC)-2-DEOXYSTREPTAMINE

There total 1 articles about BIS(N-BOC)-2-DEOXYSTREPTAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 2037-48-1,731753-11-0
2-deoxystreptamine

: 189157-45-7
((1S,2R,3R,4S,5R)-5-tert-Butoxycarbonylamino-2,3,4-trihydroxy-cyclohexyl)-carbamic acid tert-butyl ester

Guidance literature:: With triethylamine; In 1,4-dioxane; at 60 ℃; for 1h;
DOI:10.1016/S0008-6215(96)00318-7

Reference yield: 68.0%

: 3587-60-8
Benzyloxymethyl chloride

: 189157-45-7
((1S,2R,3R,4S,5R)-5-tert-Butoxycarbonylamino-2,3,4-trihydroxy-cyclohexyl)-carbamic acid tert-butyl ester

: 640749-01-5
((1S,2R,3R,4S,5R)-2,4-Bis-benzyloxymethoxy-5-tert-butoxycarbonylamino-3-hydroxy-cyclohexyl)-carbamic acid tert-butyl ester

: ((1R,2S,3R,4R,5S)-3,4-Bis-benzyloxymethoxy-5-tert-butoxycarbonylamino-2-hydroxy-cyclohexyl)-carbamic acid tert-butyl ester

Guidance literature:: With tetra-(n-butyl)ammonium iodide; N-ethyl-N,N-diisopropylamine; at 80 ℃;
DOI:10.1016/j.bmcl.2003.09.005

Reference yield:

: 189157-45-7
((1S,2R,3R,4S,5R)-5-tert-Butoxycarbonylamino-2,3,4-trihydroxy-cyclohexyl)-carbamic acid tert-butyl ester

: C₂₂H₄₈N₆O₈

Guidance literature:: Multi-step reaction with 5 steps

1: 68 percent / iPr₂NEt; TBAI / 80 °C

2: 85 percent / NaH / dimethylformamide

3: ethanol / Heating

4: ethanol / Heating

5: HCl / dioxane

With hydrogenchloride; tetra-(n-butyl)ammonium iodide; sodium hydride; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; ethanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2003.09.005