4,6-Diaminocyclohexane-1,2,3-triol

Base Information

Chemical Name:4,6-Diaminocyclohexane-1,2,3-triol
CAS No.:2037-48-1
Molecular Formula:C6H14N2O3
Molecular Weight:162.189
Hs Code.:2922199090
NSC Number:156938
Wikidata:Q104988263
Mol file:2037-48-1.mol

Synonyms:4,6-diaminocyclohexane-1,2,3-triol;NSC-156938;SCHEMBL11044942;SCHEMBL21105130;NSC156938;1,3-Cyclohexanetriol, 4,6-diamino-;1,3-Diamino-4,5,6-trihydroxycyclohexane;FT-0612153

Suppliers and Price of 4,6-Diaminocyclohexane-1,2,3-triol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
2-Deoxystreptamine, Dihydrobromide
100mg
$ 403.00

Usbiological
2-Deoxystreptamine dihydrobromide
50mg
$ 340.00

Sigma-Aldrich
2-Deoxystreptamine dihydrobromide ≥97% (TLC)
500 mg
$ 334.00

Medical Isotopes, Inc.
2-Deoxystreptamine dihydrobromide 98%
500 mg
$ 590.00

Biosynth Carbosynth
2-Deoxystreptamine dihydrobromide
250 mg
$ 250.00

Biosynth Carbosynth
2-Deoxystreptamine dihydrobromide
100 mg
$ 150.00

Biosynth Carbosynth
2-Deoxystreptamine dihydrobromide
50 mg
$ 100.00

Biosynth Carbosynth
2-Deoxystreptamine dihydrobromide
25 mg
$ 65.00

Biosynth Carbosynth
2-Deoxystreptamine dihydrobromide
500 mg
$ 450.00

American Custom Chemicals Corporation
2-DEOXYSTREPTAMINE DIHYDROBROMIDE 95.00%
1G
$ 2600.00

Total 14 raw suppliers

Chemical Property of 4,6-Diaminocyclohexane-1,2,3-triol

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:273-278°C
Refractive Index:1.62
Boiling Point:310.1°Cat760mmHg
PKA:13?+-.0.70(Predicted)
Flash Point:141.3°C
PSA：112.73000
Density:1.44g/cm³
LogP:0.44420
Storage Temp.:-20°C Freezer
Solubility.:Methanol (Slightly, Heated), Water (Slightly)
XLogP3:-3.2
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:0
Exact Mass:162.10044231
Heavy Atom Count:11
Complexity:130

Purity/Quality:

99% ^*data from raw suppliers

2-Deoxystreptamine, Dihydrobromide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1C(C(C(C(C1N)O)O)O)N
General Description 2-Deoxystreptamine dihydrobromide is a neomycin derivative that exhibits antinociceptive activity in rat models of phasic, incisional, and neuropathic pain when administered intraspinally. It demonstrates efficacy in reducing mechanical allodynia and thermal hyperalgesia, with approximate ED₅₀ values of 1.05 mg (tail-flick), 0.78 mg (incisional pain), and 0.79 mg (neuropathic pain). Its antinociceptive effects are attributed to the presence of free amino groups in its structure, which may act through calcium antagonist mechanisms, as evidenced by the transient reversal of its effects by calcium chloride. Neamine, a related derivative, shows greater potency in some pain models, while structural modifications like azido group substitutions abolish activity.

Technology Process of 4,6-Diaminocyclohexane-1,2,3-triol

There total 37 articles about 4,6-Diaminocyclohexane-1,2,3-triol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%