5-Ethyl-2-hydroxybenzoic acid

Base Information

• Chemical Name: 5-Ethyl-2-hydroxybenzoic acid
• CAS No.: 51-27-4
• Molecular Formula: C9H10O3
• Molecular Weight: 166.1739
• Hs Code.: 2918290000
• DSSTox Substance ID: DTXSID701307713
• ChEMBL ID: CHEMBL3228636
• Mol file: 51-27-4.mol

Synonyms:5-ethyl-2-hydroxybenzoic acid;51-27-4;Benzoic acid, 5-ethyl-2-hydroxy-;MFCD11203618;5-Ethyl-2-hydroxybenzoicAcid;SCHEMBL418713;2-Hydroxy-5-ethylbenzoic acid;CHEMBL3228636;DTXSID701307713;AKOS005150596;MB09459;AS-32061;SY015701;CS-0208240;EN300-61481;A871325;Z367679272

Chemical Property of 5-Ethyl-2-hydroxybenzoic acid

Chemical Property:

• PSA: 57.53000
• LogP: 1.65280
• Storage Temp.: Inert atmosphere,Room Temperature
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 166.062994177
• Heavy Atom Count: 12
• Complexity: 167

Purity/Quality:

98%min ^*data from raw suppliers

5-Ethyl-2-hydroxybenzoicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC1=CC(=C(C=C1)O)C(=O)O

Technology Process of 5-Ethyl-2-hydroxybenzoic acid

There total 4 articles about 5-Ethyl-2-hydroxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Ethylphenol (123-07-9) + carbon dioxide (124-38-9,18923-20-1) → 5-ethyl-2-hydroxy-benzoic acid (51-27-4)

Guidance literature:

With sodium;

Reference yield:

5-acetylsalicylic acid (13110-96-8) → 5-ethyl-2-hydroxy-benzoic acid (51-27-4)

Guidance literature:

With hydrogenchloride; amalgamated zinc;

Reference yield:

aspirin (50-78-2,98201-60-6) → 5-ethyl-2-hydroxy-benzoic acid (51-27-4)

Guidance literature:

Multi-step reaction with 2 steps

1: aluminium chloride; nitrobenzene

2: amalgamated zinc; aqueous hydrochloric acid

With hydrogenchloride; aluminium trichloride; amalgamated zinc; nitrobenzene;

upstream raw materials:

5-acetylsalicylic acid

4-Ethylphenol

carbon dioxide

aspirin

Downstream raw materials:

5-ethyl-3-oxo-2,3-dihydrobenzo[b]furan

(2-Hydroxy-5-ethylphenyl)(5-chloro-thien-2-yl)methanone

(2-Hydroxy-5-ethylphenyl)(5-methyl-thien-2-yl)methanone

2-thenoyl-4-ethylphenol

Refernces

• 1、 -. "External preparation for skin". . . Retrieved 2008/06/13.