Piperidinium, 3-[(hydroxydiphenylacetyl)oxy]-1,1-dimethyl-, bromide, (R)-

Base Information

Chemical Name:Piperidinium, 3-[(hydroxydiphenylacetyl)oxy]-1,1-dimethyl-, bromide, (R)-
CAS No.:92842-81-4
Molecular Formula:C21H26BrNO3
Molecular Weight:420.346
Hs Code.:
Mol file:92842-81-4.mol

Synonyms:Piperidinium, 3-[(hydroxydiphenylacetyl)oxy]-1,1-dimethyl-, bromide, (3R)- (9CI);Piperidinium, 3-[(hydroxydiphenylacetyl)oxy]-1,1-dimethyl-, bromide, (R)-

Suppliers and Price of Piperidinium, 3-[(hydroxydiphenylacetyl)oxy]-1,1-dimethyl-, bromide, (R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Piperidinium, 3-[(hydroxydiphenylacetyl)oxy]-1,1-dimethyl-, bromide, (R)-

Chemical Property:

PSA：46.53000
LogP:-0.33270

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Piperidinium, 3-[(hydroxydiphenylacetyl)oxy]-1,1-dimethyl-, bromide, (R)-

There total 2 articles about Piperidinium, 3-[(hydroxydiphenylacetyl)oxy]-1,1-dimethyl-, bromide, (R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 74-83-9
methyl bromide

: 315680-06-9
(R)-1-methylpiperidin-3-yl 2-hydroxy-2,2-diphenylacetate

: 92842-81-4,88215-34-3
(3R)-3-[(hydroxy)(diphenyl)acetoxy]-1,1-dimethylpiperidinium bromide

Guidance literature:: In acetonitrile; at 20 ℃; for 5h;

Reference yield:

: 28808-26-6
(R)-3-hydroxy-1-methylpiperidine

: 76-93-7
Benzilic acid

: 92842-81-4,88215-34-3
(3R)-3-[(hydroxy)(diphenyl)acetoxy]-1,1-dimethylpiperidinium bromide

Guidance literature:: Multi-step reaction with 2 steps

1.1: 1,1'-carbonyldiimidazole / N,N-dimethyl-formamide / 0.25 h / 20 °C

1.2: 18 h / 80 °C

2.1: 1,1'-carbonyldiimidazole / acetonitrile; tetrahydrofuran / 5 h / 20 °C

With 1,1'-carbonyldiimidazole; In tetrahydrofuran; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/j.bmc.2014.04.029