3-IMIDAZOL-1-YLMETHYL-BENZOIC ACID

Base Information

Chemical Name:3-IMIDAZOL-1-YLMETHYL-BENZOIC ACID
CAS No.:135611-31-3
Molecular Formula:C11H10N2O2
Molecular Weight:202.21
Hs Code.:
Mol file:135611-31-3.mol

Synonyms:3-IMIDAZOL-1-YLMETHYL-BENZOIC ACID;ASINEX-REAG BAS 10157016;TIMTEC-BB SBB011027

Suppliers and Price of 3-IMIDAZOL-1-YLMETHYL-BENZOIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(1H-imidazol-1-ylmethyl)benzoicacid
250mg
$ 265.00

Matrix Scientific
3-Imidazol-1-ylmethyl-benzoic acid
1g
$ 485.00

AK Scientific
3-Imidazol-1-ylmethyl-benzoicacid
1g
$ 704.00

AccelPharmtech
3-(1H-imidazol-1-ylmethyl)-Benzoicacid 97.00%
25G
$ 13300.00

AccelPharmtech
3-(1H-imidazol-1-ylmethyl)-Benzoicacid 97.00%
1G
$ 3120.00

Total 2 raw suppliers

Chemical Property of 3-IMIDAZOL-1-YLMETHYL-BENZOIC ACID

Chemical Property:

PSA：55.12000
LogP:1.62960

Purity/Quality:

98%min ^*data from raw suppliers

3-(1H-imidazol-1-ylmethyl)benzoicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-IMIDAZOL-1-YLMETHYL-BENZOIC ACID

There total 6 articles about 3-IMIDAZOL-1-YLMETHYL-BENZOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 218131-31-8
methyl 3-((1H-imidazol-1-yl)methyl)benzoate

: 135611-31-3
3-(1H-imidazol-1-ylmethyl)benzoic acid

Guidance literature:: With hydrogenchloride;
DOI:10.1021/jo981835j

Reference yield:

: 1129-28-8
3-methoxycarbonylbenzyl bromide

: 135611-31-3
3-(1H-imidazol-1-ylmethyl)benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 71 percent / imidazole / dimethylformamide / 20 °C

2: aq. LiOH / tetrahydrofuran; methanol / 2 h

With 1H-imidazole; lithium hydroxide; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm0613469

Reference yield:

: 1877-71-0
benzene 1,3-dicarboxylic acid monomethyl ester

: 135611-31-3
3-(1H-imidazol-1-ylmethyl)benzoic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 92 percent / BF₃*THF / tetrahydrofuran / 0.75 h / 20 °C

2: 52 percent / PBr₃ / diethyl ether / 2 h

3: 71 percent / imidazole / dimethylformamide / 20 °C

4: aq. LiOH / tetrahydrofuran; methanol / 2 h

With 1H-imidazole; lithium hydroxide; boron trifluoride-tetrahydrofuran complex; phosphorus tribromide; In tetrahydrofuran; methanol; diethyl ether; N,N-dimethyl-formamide;
DOI:10.1021/jm0613469