Mono-methyl isophthalate

Base Information

• Chemical Name: Mono-methyl isophthalate
• CAS No.: 1877-71-0
• Molecular Formula: C9H8O4
• Molecular Weight: 180.16
• Hs Code.: 29163990
• Mol file: 1877-71-0.mol

Synonyms:3-[(Methyloxy)carbonyl]benzoic acid;Methyl3-carboxybenzoate;Methyl hydrogen isophthalate;Methyl m-carboxybenzoate;Methyl m-phthalate;Monomethyl isophthalate;1,3-Benzenedicarboxylicacid, monomethyl ester (9CI);Isophthalic acid, methyl ester (6CI,7CI);Isophthalic acid, monomethyl ester (8CI);3-(Methoxycarbonyl)benzoic acid;3-Carbomethoxybenzoic acid;

Chemical Property of Mono-methyl isophthalate

Chemical Property:

• Appearance/Colour: White to off-white crystalline powder
• Vapor Pressure: 3.6E-05mmHg at 25°C
• Melting Point: 194-196 °C(lit.)
• Refractive Index: 1.556
• Boiling Point: 339.3 °C at 760 mmHg
• PKA: 3.83±0.10(Predicted)
• Flash Point: 139.6 °C
• PSA: 63.60000
• Density: 1.288 g/cm³
• LogP: 1.17140
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: DMSO (Slightly), Methanol (Slightly), Water (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

mono-Methyl isophthalate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Exploited in the synthesis of polymer films.1 Exploited in the synthesis of polymer films.

Technology Process of Mono-methyl isophthalate

There total 39 articles about Mono-methyl isophthalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.2%

dimethyl Isophthalate (1459-93-4) → benzene 1,3-dicarboxylic acid monomethyl ester (1877-71-0)

Guidance literature:

With potassium hydroxide; In methanol; at 20 ℃; for 15h;

DOI:10.1002/ejoc.200600502

Reference yield: 94.0%

allyl methyl isophthalate → benzene 1,3-dicarboxylic acid monomethyl ester (1877-71-0)

Guidance literature:

With tert.-butylhydroperoxide; [(S,S)-N,N’-bis(3,5-di-tertbutylsalicylidene)-1,2-cyclohexanediaminato(2-)]cobalt(II); 1,1,3,3-Tetramethyldisiloxane; In ethanol; at 20 ℃; for 11h; chemoselective reaction; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.orglett.1c03185

Reference yield: 94.0%

dicobalt octacarbonyl (15226-74-1,61091-28-9,61117-58-6) + methyl 3-(trifluoromethylsulfonyloxy)benzoate (107658-28-6) → benzene 1,3-dicarboxylic acid monomethyl ester (1877-71-0)

Guidance literature:

With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium acetate; In 1,4-dioxane; water; at 20 ℃; for 16h; chemoselective reaction; Schlenk technique; Inert atmosphere;

DOI:10.1002/adsc.201600736

upstream raw materials:

dimethyl Isophthalate

3-Methoxycarbonyl-benzoateN,N,N-trimethyl-hydrazinium;

diazomethane

isophthalic acid

Downstream raw materials:

3-(methoxycarbonyl)benzoyl chloride

Isophthalsaeuremethyldecylester

Isophthalsaeuremethyldodecylester

N,N-dimethylisophthalamic acid methyl ester