3-((1R,3r,5S)-8-azabicyclo[3.2.1]octan-3-yl)benzaMide hydrochloride

Base Information

Chemical Name:3-((1R,3r,5S)-8-azabicyclo[3.2.1]octan-3-yl)benzaMide hydrochloride
CAS No.:949904-53-4
Molecular Formula:C14H19ClN2O
Molecular Weight:266.771
Hs Code.:
Mol file:949904-53-4.mol

Synonyms:3-((1R,3r,5S)-8-azabicyclo[3.2.1]octan-3-yl)benzaMide hydrochloride

Suppliers and Price of 3-((1R,3r,5S)-8-azabicyclo[3.2.1]octan-3-yl)benzaMide hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 7 raw suppliers

Chemical Property of 3-((1R,3r,5S)-8-azabicyclo[3.2.1]octan-3-yl)benzaMide hydrochloride

Chemical Property:

PSA：55.12000
LogP:3.61460

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-((1R,3r,5S)-8-azabicyclo[3.2.1]octan-3-yl)benzaMide hydrochloride

There total 5 articles about 3-((1R,3r,5S)-8-azabicyclo[3.2.1]octan-3-yl)benzaMide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 3-(8-benzyl-8-azabicyclo[3.2.1]oct-2-en-3-yl)benzamide

: 949904-53-4
3-endo-(8-azabicyclo[3.2.1]oct-3-yl)benzamide hydrochloride

: C₁₄H₁₈N₂O*ClH

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In ethanol; water; at 30 - 50 ℃; for 5h;
DOI:10.1021/acsmedchemlett.9b00406

Reference yield:

: 949902-11-8
3-endo-(8-azabicyclo[3.2.1]oct-3-yl)-benzamide

: 949904-53-4
3-endo-(8-azabicyclo[3.2.1]oct-3-yl)benzamide hydrochloride

Guidance literature:: With hydrogenchloride; In ethanol; tert-butyl methyl ether; water; for 22h;

Reference yield:

: 949903-29-1
3-endo-[8-(2,2,2-trifluoroacetyl)-8-azabicyclo[3.2.1]oct-3-yl]-benzonitrile

: 949904-53-4
3-endo-(8-azabicyclo[3.2.1]oct-3-yl)benzamide hydrochloride

Guidance literature:: 3-endo-[8-(2,2,2-trifluoroacetyl)-8-azabicyclo[3.2.1]oct-3-yl]-benzonitrile; With sulfuric acid; water; at 50 ℃; for 2h;

With sodium hydroxide; In methanol; water; at 10 - 22 ℃; for 1h;

With hydrogenchloride; In ethanol; water;