Ethyl 2-[(4-methoxyphenoxy)methyl]-1,3-thiazole-4-carboxylate

Base Information

Chemical Name:Ethyl 2-[(4-methoxyphenoxy)methyl]-1,3-thiazole-4-carboxylate
CAS No.:262855-35-6
Molecular Formula:C₁₄H₁₅NO₄S
Molecular Weight:293.343
Hs Code.:
DSSTox Substance ID:DTXSID901331588
ChEMBL ID:CHEMBL1508721

Synonyms:MLS000859538;ethyl 2-[(4-methoxyphenoxy)methyl]-1,3-thiazole-4-carboxylate;SMR000461315;262855-35-6;Maybridge1_008390;Oprea1_391342;SCHEMBL7071567;CHEMBL1508721;BDBM47996;cid_2744008;HMS565F08;DTXSID901331588;HMS2806B04;FT-0743069;2-[(4-methoxyphenoxy)methyl]-4-thiazolecarboxylic acid ethyl ester;2-[(4-methoxyphenoxy)methyl]thiazole-4-carboxylic acid ethyl ester

Suppliers and Price of Ethyl 2-[(4-methoxyphenoxy)methyl]-1,3-thiazole-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Ethyl 2-[(4-methoxyphenoxy)methyl]-1,3-thiazole-4-carboxylate

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:293.07217913
Heavy Atom Count:20
Complexity:308

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CSC(=N1)COC2=CC=C(C=C2)OC

Technology Process of Ethyl 2-[(4-methoxyphenoxy)methyl]-1,3-thiazole-4-carboxylate

There total 1 articles about Ethyl 2-[(4-methoxyphenoxy)methyl]-1,3-thiazole-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 35370-92-4
2-(4-methoxy-phenoxy)-thioacetamide

: 673476-96-5
(2-chloro-phenyl)-thioacetic acid amide

: 262855-35-6
2-(4-methoxy-phenoxymethyl)-thiazole-4-carboxylic acid ethyl ester

Guidance literature:: In ethanol; at 75 ℃;
DOI:10.1016/S0960-894X(03)00726-1

Reference yield:

: 262855-35-6
2-(4-methoxy-phenoxymethyl)-thiazole-4-carboxylic acid ethyl ester

: 400776-21-8
2-(4-methoxy-phenoxymethyl)-thiazole-4-carboxylic acid

Guidance literature:: With potassium hydroxide; at 50 ℃;
DOI:10.1016/S0960-894X(03)00726-1

Reference yield:

: 262855-35-6
2-(4-methoxy-phenoxymethyl)-thiazole-4-carboxylic acid ethyl ester

: 2-(4-methoxy-phenoxymethyl)-thiazole-4-carbonyl azide

Guidance literature:: Multi-step reaction with 3 steps

1: aq. KOH / 50 °C

2: oxalyl chloride; DMF / CH₂Cl₂ / 20 °C

3: NaN₃ / tetrahydrofuran / 40 °C

With potassium hydroxide; sodium azide; oxalyl dichloride; N,N-dimethyl-formamide; In tetrahydrofuran; dichloromethane;
DOI:10.1016/S0960-894X(03)00726-1