(R)-2-Amino-2-(4-nitrophenyl)acetic acid

Base Information

Chemical Name:(R)-2-Amino-2-(4-nitrophenyl)acetic acid
CAS No.:336877-75-9
Molecular Formula:C₈H₈N₂O₄
Molecular Weight:196.163
Hs Code.:
DSSTox Substance ID:DTXSID70364085
Nikkaji Number:J1.964.630K

Synonyms:(R)-2-Amino-2-(4-nitrophenyl)acetic acid;336877-75-9;(2R)-2-amino-2-(4-nitrophenyl)acetic acid;D-4-Nitrophenylglycine;(R)-2-Amino-2-(4-nitrophenyl)aceticacid;DTXSID70364085;(alphaR)-alpha-Amino-4-nitrobenzeneacetic acid

Suppliers and Price of (R)-2-Amino-2-(4-nitrophenyl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 13 raw suppliers

Chemical Property of (R)-2-Amino-2-(4-nitrophenyl)acetic acid

Chemical Property:

XLogP3:-1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:196.04840674
Heavy Atom Count:14
Complexity:230

Purity/Quality:: 98%,99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(C(=O)O)N)[N+](=O)[O-]
Isomeric SMILES:C1=CC(=CC=C1[C@H](C(=O)O)N)[N+](=O)[O-]

Technology Process of (R)-2-Amino-2-(4-nitrophenyl)acetic acid

There total 7 articles about (R)-2-Amino-2-(4-nitrophenyl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 875-74-1
(R)-phenylglycine

: 336877-75-9
2-amino-2-(4-nitrophenyl)acetic acid

Guidance literature:: With sulfuric acid; nitric acid; at 0 - 5 ℃; for 0.5h;

Reference yield:

: 24113-00-6
4-N-acetylnitrophenylglycine

: 336877-75-9
2-amino-2-(4-nitrophenyl)acetic acid

Guidance literature:: 4-N-acetylnitrophenylglycine; With hydrogenchloride; water; at 100 ℃; for 3.5h;

With sodium carbonate; In water; at 20 ℃; pH=10;

Reference yield:

: 555-16-8
4-nitrobenzaldehdye

: 336877-75-9
2-amino-2-(4-nitrophenyl)acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 96 percent / acetic acid / propan-2-ol

2: tin tetrachloride / triethylamine / CH₂Cl₂ / -18 °C

3: HCl / formic acid / 20 °C

With hydrogenchloride; tin(IV) chloride; acetic acid; triethylamine; In formic acid; dichloromethane; isopropyl alcohol; 2: Strecker reaction;
DOI:10.1080/00304940509355402