Methyl 3-[2-Methoxy-4-(o-tolylsulfonylcarbaMoyl)benzyl]-

Base Information

Chemical Name:Methyl 3-[2-Methoxy-4-(o-tolylsulfonylcarbaMoyl)benzyl]-
CAS No.:1159195-67-1
Molecular Formula:C27H27N3O6S
Molecular Weight:521.594
Hs Code.:
Mol file:1159195-67-1.mol

Synonyms:Decyclopentyl Zafirlukast Methyl Ester;Methyl 3-[2-Methoxy-4-(o-tolylsulfonylcarbaMoyl)benzyl]-;N-[3-[[2-Methoxy-4-[[[(2-Methylphenyl)sulfonyl]aMino]carbonyl]phenyl]Methyl]-1-Methyl-1H-indol-5-yl]carbaMic Acid Methyl Ester;Zafirlukast Related CoMpound C

Suppliers and Price of Methyl 3-[2-Methoxy-4-(o-tolylsulfonylcarbaMoyl)benzyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
DecyclopentylZafirlukastMethylEster
100mg
$ 1320.00

Total 3 raw suppliers

Chemical Property of Methyl 3-[2-Methoxy-4-(o-tolylsulfonylcarbaMoyl)benzyl]-

Chemical Property:

Melting Point:118-122 °C
PKA:4.95±0.10(Predicted)
PSA：131.09000
Density:1.31±0.1 g/cm3(Predicted)
LogP:6.05230

Purity/Quality:

95% ^*data from raw suppliers

DecyclopentylZafirlukastMethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Decyclopentyl Zafirlukast Methyl Ester is an impurity of the cysteinyl leukotriene type 1 receptor antagonist, Zafirlukast (D226955).

Technology Process of Methyl 3-[2-Methoxy-4-(o-tolylsulfonylcarbaMoyl)benzyl]-

There total 1 articles about Methyl 3-[2-Methoxy-4-(o-tolylsulfonylcarbaMoyl)benzyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 88-19-7
methyl 2-(aminosulfonyl)benzoate

: 29906-67-0
1-methyl-5-nitro-1H-indole

: 50715-28-1
cyclopentyl chloroformate

: 70264-94-7
methyl 4-(bromomethyl)-3-methoxybenzoate

: 1159195-67-1
{3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-benzyl]-1-methyl-1H-indol-5-yl}-carbamic acid methyl ester

: 1160235-24-4
C₄₆H₄₉N₅O₈S

: 1160235-26-6
C₄₇H₄₈N₄O₁₀S₂

: 107753-78-6
ZAFIRLUKAST

Guidance literature:: 1-methyl-5-nitro-1H-indole; methyl 4-(bromomethyl)-3-methoxybenzoate; With copper(I) oxide; In 1,4-dioxane; at 95 - 100 ℃; Large scale reaction;

With hydrogen; In ethyl acetate; at 25 - 30 ℃; under 3677.86 - 4413.43 Torr; Large scale reaction;

methyl 2-(aminosulfonyl)benzoate; cyclopentyl chloroformate; Further stages;
DOI:10.1021/op800137b