Empagliflozin Impurity C

Base Information

Chemical Name:Empagliflozin Impurity C
CAS No.:864070-43-9
Molecular Formula:C₂₃H₂₇ClO₇
Molecular Weight:450.916
Hs Code.:
UNII:RU69F6Q4ZE
ChEMBL ID:CHEMBL4521016
DSSTox Substance ID:DTXSID701113221
Nikkaji Number:J3.450.204H
Mol file:864070-43-9.mol

Synonyms:864070-43-9;3'-Epi Empagliflozin;Empagliflozin Impurity C;Empagliflozin (R)-Isomer;(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((R)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;RU69F6Q4ZE;CHEMBL4521016;(2S,3R,4R,5S,6R)-2-[4-chloro-3-[[4-[(3R)-oxolan-3-yl]oxyphenyl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol;D-Glucitol, 1,5-anhydro-1-C-(4-chloro-3-((4-(((3R)-tetrahydro-3-furanyl)oxy)phenyl)methyl)phenyl)-, (1S)-;3'''-Epi-Empagliflozin;UNII-RU69F6Q4ZE;SCHEMBL899557;DTXSID701113221;BDBM50510994;(1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[[(3R)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol;CS-0165053;FT-0774380;(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((R)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (Empagliflozin Impurity pound(c)

Suppliers and Price of Empagliflozin Impurity C

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3’’’-Epi-Empagliflozin
25mg
$ 1395.00

Crysdot
(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((R)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 97%
1g
$ 297.00

Crysdot
(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((R)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 97%
5g
$ 892.00

American Custom Chemicals Corporation
3-EPI EMPAGLIFLOZIN 95.00%
5MG
$ 458.73

Alichem
(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((R)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
5g
$ 936.00

Total 12 raw suppliers

Chemical Property of Empagliflozin Impurity C

Chemical Property:

Boiling Point:664.5±55.0 °C(Predicted)
PKA:13.23±0.70(Predicted)
Density:1.398±0.06 g/cm3(Predicted)
XLogP3:2
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:6
Exact Mass:450.1445309
Heavy Atom Count:31
Complexity:558

Purity/Quality:

97% ^*data from raw suppliers

3’’’-Epi-Empagliflozin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1COCC1OC2=CC=C(C=C2)CC3=C(C=CC(=C3)C4C(C(C(C(O4)CO)O)O)O)Cl
Isomeric SMILES:C1COC[C@@H]1OC2=CC=C(C=C2)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)Cl
Uses 3’’’-Epi-Empagliflozin is an impurity of Empagliflozin (E521510) which is a novel, potent and selective SGLT-2 inhibitor, improves glycaemic control and features of metabolic syndrome in diabetic rats.

Technology Process of Empagliflozin Impurity C

There total 156 articles about Empagliflozin Impurity C which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.8%