1H-pyrimido[4,5-b]indole-2,4(3H,9H)-dione

Base Information

Chemical Name:1H-pyrimido[4,5-b]indole-2,4(3H,9H)-dione
CAS No.:115127-16-7
Molecular Formula:C₁₀H₇N₃O₂
Molecular Weight:201.184
Hs Code.:2933990090
Mol file:115127-16-7.mol

Synonyms:1H-pyrimido[4,5-b]indole-2,4(3H,9H)-dione;1,9-dihydropyrimido[6,5-b]indole-2,4-dione;1,9-dihydropyrimido[6,5-b]indole-2,4-quinone;9H-Pyrimido[4,5-b]indole-2,4-diol;AIDS148469;AIDS-148469;NCI60_028828;NSC680815

Suppliers and Price of 1H-pyrimido[4,5-b]indole-2,4(3H,9H)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1H-Pyrimido[4,5-b]indole-2,4(3H,9H)-dione 95%
1g
$ 972.00

American Custom Chemicals Corporation
1H-PYRIMIDO[4,5-B]INDOLE-2,4(3H,9H)-DIONE 95.00%
5MG
$ 497.27

AccelPharmtech
1H-Pyrimido[4,5-b]indole-2,4(3H,9H)-dione 97.00%
25G
$ 7910.00

AccelPharmtech
1H-Pyrimido[4,5-b]indole-2,4(3H,9H)-dione 97.00%
5G
$ 4220.00

AccelPharmtech
1H-Pyrimido[4,5-b]indole-2,4(3H,9H)-dione 97.00%
1G
$ 2460.00

Total 2 raw suppliers

Chemical Property of 1H-pyrimido[4,5-b]indole-2,4(3H,9H)-dione

Chemical Property:

PSA：81.51000
LogP:0.69770

Purity/Quality:

98%min ^*data from raw suppliers

1H-Pyrimido[4,5-b]indole-2,4(3H,9H)-dione 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-pyrimido[4,5-b]indole-2,4(3H,9H)-dione

There total 8 articles about 1H-pyrimido[4,5-b]indole-2,4(3H,9H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 115127-15-6
1,3-dibenzyl-1H-pyrimido<4,5-b>indole-2,4(3H,9H)-dione

: 115127-16-7
1H-pyrimido<4,5-b>indole-2,4(3H,9H)-dione

Guidance literature:: With hydrogen; palladium on activated charcoal; In acetic acid; N,N-dimethyl-formamide; for 5h; Heating;
DOI:10.1007/BF00810091

Reference yield: 88.0%

: 124-38-9,18923-20-1
carbon dioxide

: C₁₁H₉N₃O

: 115127-16-7
1H-pyrimido<4,5-b>indole-2,4(3H,9H)-dione

Guidance literature:: With 1,5-diazabicyclo[4.3.0]non-5-ene 2,2,2-trifluoroethanol; at 90 ℃; for 18h;

Reference yield:

: 2613-89-0
phenylmalonic acid

: 115127-16-7
1H-pyrimido<4,5-b>indole-2,4(3H,9H)-dione

Guidance literature:: Multi-step reaction with 5 steps

1: 72 percent / acetic anhydride, trifluoro acetic acid / CHCl₃; acetic acid / 4 h / 80 °C

2: 91 percent / POCl₃ / 8 h / Heating

3: 71 percent / NaN₃ / dimethylformamide / 12 h / Ambient temperature

4: 87 percent / xylene / 0.5 h / Heating

5: 89 percent / H₂ / Pd/C(10percent) / acetic acid; dimethylformamide / 5 h / Heating

With sodium azide; hydrogen; acetic anhydride; trifluoroacetic acid; trichlorophosphate; palladium on activated charcoal; In chloroform; acetic acid; N,N-dimethyl-formamide; xylene;
DOI:10.1007/BF00810091