2613-89-0Relevant articles and documents
Ni-Catalyzed enantioselective reductive arylcyanation/cyclization of: N -(2-iodo-aryl) acrylamide
Dong, Kaiwu,Ren, Xinyi,Shen, Chaoren,Wang, Guangzhu
, p. 1135 - 1138 (2022/02/03)
A Ni/(S,S)-BDPP-catalyzed intramolecular Heck cyclization of N-(2-iodo-aryl) acrylamide with 2-methyl-2-phenylmalononitrile was developed to give oxindoles with good enantioselectivities. We found that utilizing such an electrophilic cyanation reagent cou
Pyrimidinium compound, and preparation method and application thereof
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Paragraph 0031-0035, (2020/06/05)
The invention relates to a pyrimidinium compound, and a preparation method and an application thereof, and concretely relates to a pyrimidinium compound represented by formula (B2-A) or a stereoisomer, a nitrogen oxide and a salt thereof, an application of the above compounds as insecticides in agriculture, a form of an insecticide composition of the compound, and a method for controlling pests byusing the compounds or the composition. In the formula (B2-A), U, L, R, R, R, R, R, R, R, o and w have the meanings described in the invention.
Asymmetric Synthesis of α-Trifluoromethylthio-β-Amino Acids under Phase Transfer Catalysis
Capaccio, Vito,Sicignano, Marina,Rodríguez, Ricardo I.,Della Sala, Giorgio,Alemán, José
supporting information, p. 219 - 223 (2019/12/30)
The first asymmetric α-trifluoromethylthiolation of 2-substituted isoxazolidin-5-ones was developed using Maruoka type N-spiro ammonium catalysts under phase-transfer conditions. The resulting products, containing a trifluoromethylthiolated quaternary chiral carbon, were obtained in moderate to good yields and up to 98:2 enantiomeric ratio. Moreover, the easy N-O bond cleavage provided access to undescribed α-trifluoromethylthio-β2,2-amino acids, with promising applications in biochemistry and medicinal chemistry.