METHYL 2-AMINO-3,6-DIMETHOXYBENZOATE

Base Information

Chemical Name:METHYL 2-AMINO-3,6-DIMETHOXYBENZOATE
CAS No.:116324-66-4
Molecular Formula:C10H13NO4
Molecular Weight:196.203
Hs Code.:2918990090
Mol file:116324-66-4.mol

Synonyms:METHYL 2-AMINO-3,6-DIMETHOXYBENZOATE;3,6-diMethoxy-2-Methylbenzoic acid

Suppliers and Price of METHYL 2-AMINO-3,6-DIMETHOXYBENZOATE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3,6-Dimethoxy-2-methylbenzoicacid 95+%
1g
$ 455.00

American Custom Chemicals Corporation
2,5-DIMETHOXY-6-METHYLBENZOIC ACID 95.00%
5MG
$ 501.47

Alichem
3,6-Dimethoxy-2-methylbenzoicacid
5g
$ 1783.96

Alichem
3,6-Dimethoxy-2-methylbenzoicacid
1g
$ 480.15

Alichem
3,6-Dimethoxy-2-methylbenzoicacid
250mg
$ 215.82

Total 5 raw suppliers

Chemical Property of METHYL 2-AMINO-3,6-DIMETHOXYBENZOATE

Chemical Property:

Vapor Pressure:6.72E-05mmHg at 25°C
Boiling Point:344.1°C at 760 mmHg
PKA:3.62±0.31(Predicted)
Flash Point:167.1°C
PSA：55.76000
Density:1.189g/cm³
LogP:1.71040

Purity/Quality:

98%min ^*data from raw suppliers

3,6-Dimethoxy-2-methylbenzoicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of METHYL 2-AMINO-3,6-DIMETHOXYBENZOATE

There total 5 articles about METHYL 2-AMINO-3,6-DIMETHOXYBENZOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 121625-00-1
3,6-dimethoxyl-2-methylbenzaldehyde

: 116324-66-4
2,5-Dimethoxy-6-methylbenzoesaeure

Guidance literature:: With sodium chlorite; sodium dihydrogen phosphate monohydrate; 2-methyl-but-2-ene; In water; tert-butyl alcohol; at 0 ℃; for 1h;
DOI:10.1021/acs.orglett.8b04044

Reference yield:

: 2785-98-0
2,5-dimethoxybenzoic acid

: 74-88-4
methyl iodide

: 116324-66-4
2,5-Dimethoxy-6-methylbenzoesaeure

Guidance literature:: 2,5-dimethoxybenzoic acid; With 2,2,6,6-tetramethyl-piperidine; n-butyllithium; In tetrahydrofuran; at 0 ℃; for 2.5h;

methyl iodide; In tetrahydrofuran; at 25 ℃; for 2h;

Reference yield:

: 93-02-7
2,5-dimethoxybenzaldehyde

: 116324-66-4
2,5-Dimethoxy-6-methylbenzoesaeure

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium N-methyl-N-(N',N'-dimethyl-2-aminoethyl)amide; phenyllithium / benzene / 23 °C / Inert atmosphere

1.2: 23 °C / Inert atmosphere

2.1: sodium dihydrogenphosphate; sodium chlorite; 2-methyl-but-2-ene / water; tert-butyl alcohol / 0 °C / Inert atmosphere

With sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; lithium N-methyl-N-(N',N'-dimethyl-2-aminoethyl)amide; phenyllithium; In water; tert-butyl alcohol; benzene;
DOI:10.1002/chem.201002157