Tetraethyl (4-aMinophenyl)-1,3-diphosphonate

Base Information

• Chemical Name: Tetraethyl (4-aMinophenyl)-1,3-diphosphonate
• CAS No.: 245111-14-2
• Molecular Formula: C₁₄H₂₅NO₆P₂
• Molecular Weight: 365.303
• Mol file: 245111-14-2.mol

Synonyms:Aniline-2,4-diphosphonic acid tetraethyl ester;Tetraethyl (4-aMinophenyl)-1,3-diphosphonate;P,P''-(4-aMino-1,3-phenylene)bisphosphonic acid P,P,P',P'-tetraethyl ester

Chemical Property of Tetraethyl (4-aMinophenyl)-1,3-diphosphonate

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Tetraethyl(4-amino-1,3-phenylene)bis(phosphonate) 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Tetraethyl (4-aMinophenyl)-1,3-diphosphonate

There total 3 articles about Tetraethyl (4-aMinophenyl)-1,3-diphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.8%

2,4-dibromo-aniline (615-57-6) + phosphonic acid diethyl ester (762-04-9) → 2,4-bis(diethoxyphosphinoyl)aniline (245111-14-2)

Guidance literature:

With N-Methyldicyclohexylamine; palladium diacetate; triphenylphosphine; In ethanol; for 48h; Reflux; Inert atmosphere;

DOI:10.1002/pola.24422

Reference yield: 53.0%

2,4-dibromo-aniline (615-57-6) + phosphonic acid diethyl ester (762-04-9) → diethyl phenylphosphonate (1754-49-0) + diethyl (4-aminophenyl)phosphonate (42822-57-1) + 2,4-bis(diethoxyphosphinoyl)aniline (245111-14-2)

Guidance literature:

With N-Methyldicyclohexylamine; palladium diacetate; triphenylphosphine; In ethanol; for 48h; Reflux; Inert atmosphere;

DOI:10.1246/cl.2009.738

Reference yield:

2,4-dibromo-aniline (615-57-6) + phosphonic acid diethyl ester (762-04-9) → diethyl (4-aminophenyl)phosphonate (42822-57-1) + (2-aminophenyl)phosphonic acid diethyl ester (31238-50-3) + 2,4-bis(diethoxyphosphinoyl)aniline (245111-14-2)

Guidance literature:

phosphonic acid diethyl ester; With potassium tert-butylate; In N,N-dimethyl-formamide; at 20 ℃; for 0.166667h;

2,4-dibromo-aniline; In N,N-dimethyl-formamide; at 20 ℃; for 5h; Irradiation;

DOI:10.1055/s-1999-3553

upstream raw materials:

2,4-dibromo-aniline

phosphonic acid diethyl ester