2-Amino-N,3-diphenylpropanamide hydrochloride

Base Information

• Chemical Name: 2-Amino-N,3-diphenylpropanamide hydrochloride
• CAS No.: 857770-81-1
• Molecular Formula: C₁₅H₁₆N₂O*2ClH
• Molecular Weight: 313.227
• Hs Code.: 2924299090
• Mol file: 857770-81-1.mol

Synonyms:2-Amino-N,3-diphenylpropanamide hydrochloride

Chemical Property of 2-Amino-N,3-diphenylpropanamide hydrochloride

Chemical Property:

• PSA: 55.12000
• LogP: 3.77040

Purity/Quality:

98%min ^*data from raw suppliers

2-Amino-N,3-diphenylpropanamide hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Amino-N,3-diphenylpropanamide hydrochloride

There total 4 articles about 2-Amino-N,3-diphenylpropanamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

→ (S)-phenylalanine-phenylamide hydrochloride (126090-44-6,857770-81-1)

Guidance literature:

Reference yield:

aniline (62-53-3) → C15H16N2O*2ClH (857770-81-1)

Guidance literature:

Multi-step reaction with 2 steps

1: dicyclohexyl-carbodiimide / tetrahydrofuran / Inert atmosphere; Cooling with ice

2: hydrogenchloride / methanol

With hydrogenchloride; dicyclohexyl-carbodiimide; In tetrahydrofuran; methanol;

DOI:10.1002/asia.201402053

Reference yield:

N2-<(tert-butoxy)carbonyl>-L-phenylalanine phenylamide (113035-40-8) → C15H16N2O*2ClH (857770-81-1)

Guidance literature:

With hydrogenchloride; In methanol;

DOI:10.1002/asia.201402053

upstream raw materials:

aniline

N²-<(tert-butoxy)carbonyl>-L-phenylalanine phenylamide

N-tert-butoxycarbonyl-L-phenylalanine

Downstream raw materials:

(S)-N-benzoyl-phenylalanine anilide