6-Fluoro-1H-indole-2-carbaldehyde

Base Information

Chemical Name:6-Fluoro-1H-indole-2-carbaldehyde
CAS No.:933746-81-7
Molecular Formula:C₉H₆FNO
Molecular Weight:163.151
Hs Code.:
European Community (EC) Number:878-231-9
DSSTox Substance ID:DTXSID70699627
Wikidata:Q82630619
Mol file:933746-81-7.mol

Synonyms:6-FLUORO-1H-INDOLE-2-CARBALDEHYDE;933746-81-7;SCHEMBL2548885;DTXSID70699627;AMY24421;6-fluoro-1h-indole-2-carboxaldehyde;MFCD11040760;AKOS006306295;NS-01288;CS-0131061;E81533;EN300-178396;Z1198305780

Suppliers and Price of 6-Fluoro-1H-indole-2-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
6-Fluoro-1H-indole-2-carbaldehyde
250mg
$ 513.00

Alichem
6-Fluoro-1H-indole-2-carbaldehyde
1g
$ 759.00

American Custom Chemicals Corporation
6-FLUORO-1H-INDOLE-2-CARBALDEHYDE 95.00%
5MG
$ 505.09

Chemenu
6-Fluoro-1H-indole-2-carbaldehyde 95%
1g
$ 645.00

Crysdot
6-Fluoro-1H-indole-2-carbaldehyde 95+%
1g
$ 683.00

TRC
6-Fluoro-1H-indole-2-carbaldehyde
10mg
$ 45.00

Total 8 raw suppliers

Chemical Property of 6-Fluoro-1H-indole-2-carbaldehyde

Chemical Property:

PSA：32.86000
LogP:2.11950
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:163.043341977
Heavy Atom Count:12
Complexity:185

Purity/Quality:

97% ^*data from raw suppliers

6-Fluoro-1H-indole-2-carbaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=C1F)NC(=C2)C=O

Technology Process of 6-Fluoro-1H-indole-2-carbaldehyde

There total 7 articles about 6-Fluoro-1H-indole-2-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 884048-32-2
(6-fluoro-1H-indol-2-yl)methanol

: 933746-81-7
6-fluoro-1H-indole-2-carbaldehyde

Guidance literature:: With manganese(IV) oxide; In N,N-dimethyl-formamide; at 20 ℃; for 12h; Inert atmosphere;
DOI:10.1016/j.ejmech.2016.05.065

Reference yield: 90.0%

: 6-fluoro-1-(phenylsulfonyl)-1H-indole-2-carbaldehyde

: 933746-81-7
6-fluoro-1H-indole-2-carbaldehyde

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 12h;

Reference yield:

: 348-37-8
6-fluoro-1H-indole-2-carboxylic acid ethyl ester

: 933746-81-7
6-fluoro-1H-indole-2-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 3.5 h / 0 °C / Inert atmosphere; Schlenk technique

2: manganese(IV) oxide / dichloromethane / 12 h / 10 - 20 °C / Inert atmosphere; Schlenk technique

With manganese(IV) oxide; lithium aluminium tetrahydride; In tetrahydrofuran; dichloromethane;
DOI:10.1021/acs.orglett.9b01624