ethyl 6-fluoro-1H-indole-2-carboxylate

Base Information

Chemical Name:ethyl 6-fluoro-1H-indole-2-carboxylate
CAS No.:348-37-8
Molecular Formula:C11H10FNO2
Molecular Weight:207.204
Hs Code.:2933990090
DSSTox Substance ID:DTXSID70572087
Nikkaji Number:J1.080.921E
Wikidata:Q72474897
Mol file:348-37-8.mol

Synonyms:348-37-8;ethyl 6-fluoro-1H-indole-2-carboxylate;Ethyl 6-fluoroindole-2-carboxylate;6-Fluoroindole-2-carboxylic acid ethyl ester;1H-Indole-2-carboxylic acid, 6-fluoro-, ethyl ester;MFCD03095203;SCHEMBL2465902;AMY3953;DTXSID70572087;KOLXHQLPMICACW-UHFFFAOYSA-N;ethyl 6-fluoro-2-indolecarboxylate;AKOS009160429;SB15261;DS-17492;SY040110;CS-0043037;F-5302;A822426;Ethyl 6-fluoro-1H-indole-2-carboxylate, AldrichCPR;Ethyl 6-Fluoroindole-2-carboxylate

Suppliers and Price of ethyl 6-fluoro-1H-indole-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl6-Fluoro-1H-indole-2-carboxylate
50mg
$ 45.00

SynQuest Laboratories
Ethyl 6-fluoroindole-2-carboxylate
5 g
$ 436.00

SynQuest Laboratories
Ethyl 6-fluoroindole-2-carboxylate
1 g
$ 95.00

Oakwood
Ethyl6-fluoro-1H-indole-2-carboxylate 95+%
1g
$ 108.00

Matrix Scientific
Ethyl6-fluoro-1H-indole-2-carboxylate 97.0%
1g
$ 149.00

Crysdot
Ethyl6-fluoro-1H-indole-2-carboxylate 97%
10g
$ 400.00

Chemenu
ethyl6-fluoro-1H-indole-2-carboxylate 95%+
10g
$ 352.00

Chemenu
ethyl6-fluoro-1H-indole-2-carboxylate 95%+
25g
$ 616.00

Chemenu
ethyl6-fluoro-1H-indole-2-carboxylate 95%+
5g
$ 216.00

Apolloscientific
Ethyl6-fluoro-1H-indole-2-carboxylate
1g
$ 59.00

Total 52 raw suppliers

Chemical Property of ethyl 6-fluoro-1H-indole-2-carboxylate

Chemical Property:

Melting Point:143 °C
Boiling Point:345.872 °C at 760 mmHg
PKA:14.41±0.30(Predicted)
Flash Point:162.978 °C
PSA：42.09000
Density:1.291 g/cm³
LogP:2.48370
Storage Temp.:Sealed in dry,Room Temperature
Sensitive.:Light Sensitive
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:207.06955672
Heavy Atom Count:15
Complexity:247

Purity/Quality:

99%, ^*data from raw suppliers

Ethyl6-Fluoro-1H-indole-2-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC2=C(N1)C=C(C=C2)F

Technology Process of ethyl 6-fluoro-1H-indole-2-carboxylate

There total 16 articles about ethyl 6-fluoro-1H-indole-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.1%

: 3093-97-8
6-fluoro-1H-indole-2-carboxylic acid

: 64-17-5
ethanol

: 348-37-8
6-fluoro-1H-indole-2-carboxylic acid ethyl ester

Guidance literature:: With sulfuric acid; at 105 ℃; for 2h;

Reference yield: 81.0%

: 346-43-0
ethyl (4-fluoro-2-nitrophenyl)pyruvate

: 348-37-8
6-fluoro-1H-indole-2-carboxylic acid ethyl ester

Guidance literature:: With iron; In ethanol; acetic acid; for 3.5h; Heating / reflux;

Reference yield: 72.0%

: 59142-68-6
2-bromo-4-fluorobenzaldehyde

: 623-33-6
glycine ethyl ester hydrochloride

: 348-37-8
6-fluoro-1H-indole-2-carboxylic acid ethyl ester

Guidance literature:: With copper(I) oxide; caesium carbonate; In 1-methyl-pyrrolidin-2-one; at 100 ℃; for 16h; Inert atmosphere; Sealed tube;
DOI:10.1002/ejoc.201301607 DOI:10.1002/ejoc.201301607