Technology Process of 3-[4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)phenoxy]-2,6-dimethylpyridine
There total 5 articles about 3-[4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)phenoxy]-2,6-dimethylpyridine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate;
In
dimethyl sulfoxide;
at 117 ℃;
for 5h;
DOI:10.1021/jm2016864
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: caesium carbonate / N,N-dimethyl-formamide / 0.5 h / 170 °C / Microwave irradiation
2.1: palladium 10% on activated carbon; hydrogen / ethyl acetate / 20 °C
3.1: hydrogen bromide; sodium nitrite / water / 2 h / 0 - 20 °C
3.2: 0 - 140 °C
4.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / dimethyl sulfoxide / 5 h / 117 °C
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; palladium 10% on activated carbon; hydrogen bromide; hydrogen; potassium acetate; caesium carbonate; sodium nitrite;
In
water; dimethyl sulfoxide; ethyl acetate; N,N-dimethyl-formamide;
3.2: Sandmeyer reaction;
DOI:10.1021/jm2016864
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: palladium 10% on activated carbon; hydrogen / ethyl acetate / 20 °C
2.1: hydrogen bromide; sodium nitrite / water / 2 h / 0 - 20 °C
2.2: 0 - 140 °C
3.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / dimethyl sulfoxide / 5 h / 117 °C
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; palladium 10% on activated carbon; hydrogen bromide; hydrogen; potassium acetate; sodium nitrite;
In
water; dimethyl sulfoxide; ethyl acetate;
2.2: Sandmeyer reaction;
DOI:10.1021/jm2016864
