Aramchol

Base Information

Chemical Name:Aramchol
CAS No.:246529-22-6
Molecular Formula:C44H79NO5
Molecular Weight:702.1
Hs Code.:
UNII:QE1Q24M65Y
ChEMBL ID:CHEMBL4297262
DSSTox Substance ID:DTXSID90179395
Metabolomics Workbench ID:152947
NCI Thesaurus Code:C188616
Nikkaji Number:J1.650.664H
Wikidata:Q19903337
Wikipedia:Aramchol
Mol file:246529-22-6.mol

Synonyms:(3beta,5beta,7alpha,12alpha)-7,12-dihydroxy-3-(icosanoylamino)cholan-24-oic acid;arachidyl amido cholanoic acid;aramchol

Suppliers and Price of Aramchol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Aramchol
100mg
$ 315.00

Cayman Chemical
Aramchol ≥95%
25mg
$ 616.00

Cayman Chemical
Aramchol ≥95%
10mg
$ 303.00

Cayman Chemical
Aramchol ≥95%
5mg
$ 171.00

Cayman Chemical
Aramchol ≥95%
1mg
$ 39.00

AK Scientific
Aramchol
5mg
$ 313.00

Total 16 raw suppliers

Chemical Property of Aramchol

Chemical Property:

Boiling Point:806.0±65.0 °C(Predicted)
PKA:4.76±0.10(Predicted)
PSA：110.35000
Density:1.05±0.1 g/cm3(Predicted)
LogP:11.45460
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:13.1
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:23
Exact Mass:701.59582462
Heavy Atom Count:50
Complexity:1020

Purity/Quality:

99% ^*data from raw suppliers

Aramchol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCCCCCCCCCCCCCCC(=O)NC1CCC2(C(C1)CC(C3C2CC(C4(C3CCC4C(C)CCC(=O)O)C)O)O)C
Isomeric SMILES:CCCCCCCCCCCCCCCCCCCC(=O)N[C@H]1CC[C@]2([C@@H](C1)C[C@H]([C@@H]3[C@@H]2C[C@@H]([C@]4([C@H]3CC[C@@H]4[C@H](C)CCC(=O)O)C)O)O)C
Recent ClinicalTrials:An Open-Label, Two-Part Study Designed to Assess the Absolute Bioavailability and Mass Balance of Aramchol
Recent EU Clinical Trials:A Phase 3, Multinational, Multicenter, Double-Blind, Placebo-Controlled Clinical Study to Evaluate the Efficacy and Safety of Aramchol in Subjects with Nonalcoholic Steatohepatitis (NASH)
Uses Aramchol is a fatty acid conjugate that exhibits?hypocholesterolemic effects. Studies have shown that aramchol?suppresses the activity of?stearoyl-CoA desaturase (SCD), which leads to reduction of obesity, fatty liver and insulin resistance.

Technology Process of Aramchol

There total 15 articles about Aramchol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.8%