Chemical Property of Cholic acid
Chemical Property:
- Appearance/Colour:white to light beige crystalline powder
- Vapor Pressure:4.59E-16mmHg at 25°C
- Melting Point:200-201 °C(lit.)
- Refractive Index:1.558
- Boiling Point:583.876 °C at 760 mmHg
- PKA:4.98(at 20℃)
- Flash Point:320.956 °C
- PSA：97.99000
- Density:1.185 g/cm3
- LogP:3.44870
- Storage Temp.:Store at RT.
- Solubility.:methanol: 0.1 g/mL, clear
- Water Solubility.:0.28 g/L (15 ºC)
- XLogP3:3.6
- Hydrogen Bond Donor Count:4
- Hydrogen Bond Acceptor Count:5
- Rotatable Bond Count:4
- Exact Mass:408.28757437
- Heavy Atom Count:29
- Complexity:637
- Purity/Quality:
-
99% *data from raw suppliers
Cholic acid *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xi
- Hazard Codes:Xi
- Statements:
36/37/38
- Safety Statements:
24/25-36-26
- MSDS Files:
-
SDS file from LookChem
Useful:
- Chemical Classes:Other Classes -> Organic Acids
- Drug Classes:Gastrointestinal Agents
- Canonical SMILES:CC(CCC(=O)O)C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C
- Isomeric SMILES:C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C
- Recent ClinicalTrials:The REPLACE Registry for Cholbam? (Cholic Acid)
- Recent EU Clinical Trials:Cholic acid treatment in Peroxisomal Biogenesis Disorders (Zellweger spectrum): biochemical and clinical effects.
-
Uses
(1) Emulsifiers.
(2) Used for biochemical research, as pharmaceutical intermediates. Sodium cholate is a cholagogue, for the treatment of cholecystitis, bile deficiency, intestinal indigestion embolism.
(3) As organic acids with steroid structure, cholic acid can emulsify fat, promote its digestion.
(4) Non-denaturing ionic detergents for the extraction of membrane proteins. Choleretic produced by, and isolated from liver cells. asthma therapeutic Cholic Acid is an emulsifier that exists as colorless plates or a white
crystalline powder which has a bitter taste with a sweetish aftertaste.
it is slightly soluble in water. it functions as an emulsifying agent in
egg white.
