3-Methyl-2-butenal dimethyl hydrazone

Base Information

• Chemical Name: 3-Methyl-2-butenal dimethyl hydrazone
• CAS No.: 16713-48-7
• Molecular Formula: C7H14N2
• Molecular Weight: 126.202
• Hs Code.: 2928000090
• Mol file: 16713-48-7.mol

Synonyms:3-Methyl-2-butenal dimethyl hydrazone

Chemical Property of 3-Methyl-2-butenal dimethyl hydrazone

Chemical Property:

• PSA: 15.60000
• LogP: 1.50000

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Methyl-2-butenal dimethyl hydrazone

There total 2 articles about 3-Methyl-2-butenal dimethyl hydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

3,3-dimethyl acrylaldehyde (107-86-8) + N,N-Dimethylhydrazine (57-14-7) → 3-methyl-2-butenal dimethylhydrazone (16713-48-7)

Guidance literature:

With trifluoroacetic acid; In benzene; for 0.0666667h; Heating;

DOI:10.1246/bcsj.66.1759

Reference yield:

2-bromo-3-methyl-butyraldehyde (64932-36-1) + N,N-Dimethylhydrazine (57-14-7) → 3-methyl-2-butenal dimethylhydrazone (16713-48-7)

Guidance literature:

Reference yield:

3-methyl-2-butenal dimethylhydrazone (16713-48-7) → (+/-)-lavandulol (58461-27-1,21090-68-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) LDA / 1.) THF, 2.) THF

2: 68 percent / aq. CuCl₂ / 2.5 h / Ambient temperature

3: 66 percent / NaBH₄ / ethanol / 4 h / Ambient temperature

With sodium tetrahydroborate; copper dichloride; lithium diisopropyl amide; In ethanol;

DOI:10.1021/jo9613242

upstream raw materials:

2-bromo-3-methyl-butyraldehyde

N,N-Dimethylhydrazine

3,3-dimethyl acrylaldehyde

Downstream raw materials:

2-benzyl-3-methyl-4-hexenal dimethylhydrazone

(+/-)-lavandulol

Refernces

• 1、 Yamashita, Masakazu,Matsumiya, Kaoru,Nakano, Ken-ichi. "α-Alkylation of α,β-Unsaturated Aldehyde Dimethylhydrazones Accompanied with the Double Bond Migration to β,γ". . p. 1759 - 1763. Retrieved 2007/10/02.