4-Chloro-N-(4-methoxyphenyl)-1,2-benzenediamine

Base Information

• Chemical Name: 4-Chloro-N-(4-methoxyphenyl)-1,2-benzenediamine
• CAS No.: 1750-94-3
• Molecular Formula: C13H13ClN2O
• Molecular Weight: 248.712
• Hs Code.: 2922299090
• Mol file: 1750-94-3.mol

Synonyms:4-Chloro-N-(4-methoxyphenyl)-1,2-benzenediamine

Chemical Property of 4-Chloro-N-(4-methoxyphenyl)-1,2-benzenediamine

Chemical Property:

• PSA: 47.28000
• LogP: 4.32860

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Chloro-N-(4-methoxyphenyl)-1,2-benzenediamine

There total 3 articles about 4-Chloro-N-(4-methoxyphenyl)-1,2-benzenediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-chloro-N-(4-methoxyphenyl)-2-nitro-aniline (6373-69-9) → 4-Chloro-N1-(4-methoxyphenyl)benzene-1,2-diamine (1750-94-3)

Guidance literature:

4-chloro-N-(4-methoxyphenyl)-2-nitro-aniline; With sodium dithionite; In tetrahydrofuran; ethanol; water; at 0 - 20 ℃; for 2h;

With sodium hydrogencarbonate; In tetrahydrofuran; ethanol; water;

Reference yield:

2,5-dichloronitrobenzene (89-61-2) → 4-Chloro-N1-(4-methoxyphenyl)benzene-1,2-diamine (1750-94-3)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / 185 °C

2: iron; ammonium chloride / water; ethanol / 3 h / 90 °C

With iron; potassium carbonate; ammonium chloride; In ethanol; water;

DOI:10.1016/j.cclet.2017.04.021

Reference yield:

→ 4-Chloro-N1-(4-methoxyphenyl)benzene-1,2-diamine (1750-94-3)

Guidance literature:

Verb. /BRN= 814893/, SnCl2 in wss. HCl (Δ);

upstream raw materials:

4-chloro-N-(4-methoxyphenyl)-2-nitro-aniline

2,5-dichloronitrobenzene

Refernces

• 1、 -. "RECEPTOR FUNCTION REGULATING AGENT". Page/Page column 43. . Retrieved 2010/11/28.