(R)-tert-butyl (4-(5-(3-cyanophenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)carbamate

Base Information

Chemical Name:(R)-tert-butyl (4-(5-(3-cyanophenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)carbamate
CAS No.:1306763-71-2
Molecular Formula:
Molecular Weight:460.52
Hs Code.:
Mol file:1306763-71-2.mol

Synonyms:(R)-tert-butyl (4-(5-(3-cyanophenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)carbamate;(S)-tert-butyl (4-(5-(3-cyano-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)carbamate;tert-butyl (S)-(4-(5-(3-cyano-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)carbamate

Suppliers and Price of (R)-tert-butyl (4-(5-(3-cyanophenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 5 raw suppliers

Chemical Property of (R)-tert-butyl (4-(5-(3-cyanophenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)carbamate

Chemical Property:

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-tert-butyl (4-(5-(3-cyanophenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)carbamate

There total 17 articles about (R)-tert-butyl (4-(5-(3-cyanophenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: (R)-tert-butyl 4-(N-(3-cyano-4-isopropoxybenzolyloxy)carbamimidoyl)-2,3-dihydro-1H-inden-1-ylcarbamate

: 1306763-71-2
(R)-tert-butyl 4-(5-(3-cyano-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-ylcarbamate

Guidance literature:: In N,N-dimethyl-formamide; at 95 ℃; for 12h;

Reference yield:

: C₂₆H₃₀N₄O₄

: 1306763-71-2
(R)-tert-butyl 4-(5-(3-cyano-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-ylcarbamate

Guidance literature:: In N,N-dimethyl-formamide; at 95 ℃; for 12h;

Reference yield:

: 1306763-30-3
(R)-tert-butyl 4-cyano-2,3-dihydro-1H-inden-1-ylcarbamate

: 1306763-71-2
(R)-tert-butyl 4-(5-(3-cyano-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-ylcarbamate

Guidance literature:: Multi-step reaction with 3 steps

1.1: hydroxylamine hydrochloride; triethylamine / ethanol / 2 h / 85 °C

2.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 2 h / 20 °C / Inert atmosphere

2.2: 2 h / 20 °C

3.1: N,N-dimethyl-formamide / 12 h / 95 °C

With hydroxylamine hydrochloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In ethanol; N,N-dimethyl-formamide;