2(1H)-Pyridinone,5,6-dihydro-5,6-dihydroxy-1-methyl-,(5S,6S)-(9CI)

Base Information

• Chemical Name: 2(1H)-Pyridinone,5,6-dihydro-5,6-dihydroxy-1-methyl-,(5S,6S)-(9CI)
• CAS No.: 471248-30-3
• Molecular Formula: C₆H₉NO₃
• Molecular Weight: 143.142
• Mol file: 471248-30-3.mol

Synonyms:2(1H)-Pyridinone,5,6-dihydro-5,6-dihydroxy-1-methyl-,(5S,6S)-(9CI)

Chemical Property of 2(1H)-Pyridinone,5,6-dihydro-5,6-dihydroxy-1-methyl-,(5S,6S)-(9CI)

Chemical Property:

• PSA: 60.77000
• LogP: -1.36820

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2(1H)-Pyridinone,5,6-dihydro-5,6-dihydroxy-1-methyl-,(5S,6S)-(9CI)

There total 2 articles about 2(1H)-Pyridinone,5,6-dihydro-5,6-dihydroxy-1-methyl-,(5S,6S)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

1-methyl-2-pyridone (694-85-9,859803-97-7) → cis-3,4-dihydro-3,4-dihydroxy-1-methyl-2-pyridone (471248-31-4) + trans-5,6-dihydro-5,6-dihydroxy-1-methyl-2-pyridone (471248-32-5) + (+)-cis-(5S,6S)-1-methyl-5,6-dihydroxy-5,6-dihydro-2-pyridone (471248-30-3)

Guidance literature:

With D-glucose; Escherichia coli JM₁₀₉(DE₃)pDTG₁₄₁; In phosphate buffer; at 30 ℃; for 22h; pH=7.2;

DOI:10.1016/S0040-4039(00)00541-4

Reference yield:

1-methyl-2-pyridone (694-85-9,859803-97-7) → (+)-cis-(5S,6S)-1-methyl-5,6-dihydroxy-5,6-dihydro-2-pyridone (471248-30-3) + (+)-cis-(3S,4S)-1-methyl-3,4-dihydroxy-3,4-dihydro-2-pyridone (471248-31-4)

Guidance literature:

With E_. coli JM₁₀₉(DE₃) (pDTG₁₄₁); oxygen; Enzymatic reaction;

DOI:10.1139/v02-062

Reference yield:

(+)-cis-(5S,6S)-1-methyl-5,6-dihydroxy-5,6-dihydro-2-pyridone (471248-30-3) → 5-hydroxy-1-methylpyridin-2(1H)-one (29094-75-5)

Guidance literature:

at 60 ℃;

DOI:10.1016/S0040-4039(00)00541-4

upstream raw materials:

1-methyl-2-pyridone

Downstream raw materials:

5-hydroxy-1-methylpyridin-2(1H)-one

trans-5,6-dihydro-5,6-dihydroxy-1-methyl-2-pyridone