(S)-2-(2-Fluorophenyl)-2-hydroxyacetic acid

Base Information

Chemical Name:(S)-2-(2-Fluorophenyl)-2-hydroxyacetic acid
CAS No.:175134-34-6
Molecular Formula:C8H7FO3
Molecular Weight:170.1377832
Hs Code.:
European Community (EC) Number:870-503-5
Nikkaji Number:J841.172G
Mol file:175134-34-6.mol

Synonyms:175134-34-6;(S)-2-(2-Fluorophenyl)-2-hydroxyacetic acid;(2S)-2-(2-fluorophenyl)-2-hydroxyacetic acid;Benzeneacetic acid, a-hydroxy-2-fluoro-, (S)-;SCHEMBL11354965;(S)-2-(2-Fluorophenyl)-2-hydroxyaceticacid;(S)-alpha-Hydroxy-2-fluorobenzeneacetic acid;EN300-7851368

Suppliers and Price of (S)-2-(2-Fluorophenyl)-2-hydroxyacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (S)-2-(2-Fluorophenyl)-2-hydroxyacetic acid

Chemical Property:

PSA：57.53000
LogP:0.94370
XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:170.03792224
Heavy Atom Count:12
Complexity:172

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C(C(=O)O)O)F
Isomeric SMILES:C1=CC=C(C(=C1)[C@@H](C(=O)O)O)F

Technology Process of (S)-2-(2-Fluorophenyl)-2-hydroxyacetic acid

There total 7 articles about (S)-2-(2-Fluorophenyl)-2-hydroxyacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 394-46-7
2-fluorostyrene

: 175134-34-6
(S)-2-(2-fluorophenyl)-2-hydroxyacetic acid

Guidance literature:: With D-glucose; In aq. phosphate buffer; Hexadecane; at 30 ℃; for 12h; pH=8; Microbiological reaction;

Reference yield:

: 74-90-8
hydrogen cyanide

: 446-52-6
2-Fluorobenzaldehyde

: 175134-34-6
(S)-2-(2-fluorophenyl)-2-hydroxyacetic acid

: 389-31-1,52950-13-7,32222-48-3
R-ortho-fluoromandelic acid

Guidance literature:: 2C₃₆H₅₄N₂O₂*OV; In toluene; at 20 ℃; for 24h;

Reference yield:

: 79477-86-4
2-fluorophenylglyoxylic acid

: 175134-34-6
(S)-2-(2-fluorophenyl)-2-hydroxyacetic acid

: 389-31-1,52950-13-7,32222-48-3
R-ortho-fluoromandelic acid

Guidance literature:: With C₄₈H₅₀N₂O₂P₂Ru*2C₁₈H₁₅P*4Cl^(1-)*2Ru⁽²⁺⁾; hydrogen; sodium acetate; triphenylphosphine; In methanol; at 0 ℃; for 24h; under 30003 Torr; Overall yield = 94 %; Overall yield = 46.5 mg; enantioselective reaction; Autoclave;
DOI:10.1002/adsc.201700846