5,5'-Dimethylbiphenyl-2,2'-diamine

Base Information

• Chemical Name: 5,5'-Dimethylbiphenyl-2,2'-diamine
• CAS No.: 59594-56-8
• Molecular Formula: C14H16N2
• Molecular Weight: 212.29
• DSSTox Substance ID: DTXSID90461242
• Nikkaji Number: J90.058C
• Wikidata: Q82285516
• Mol file: 59594-56-8.mol

Synonyms:5,5'-Dimethylbiphenyl-2,2'-diamine;59594-56-8;2-(2-amino-5-methylphenyl)-4-methylaniline;SCHEMBL18131295;DTXSID90461242

Chemical Property of 5,5'-Dimethylbiphenyl-2,2'-diamine

Chemical Property:

• PSA: 52.04000
• LogP: 4.29720
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 212.131348519
• Heavy Atom Count: 16
• Complexity: 205

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1)N)C2=C(C=CC(=C2)C)N

Technology Process of 5,5'-Dimethylbiphenyl-2,2'-diamine

There total 9 articles about 5,5'-Dimethylbiphenyl-2,2'-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-iodo-4-methylaniline (29289-13-2) → 5,5′-dimethyl-[1,1′-biphenyl]-2,2′-diamine (59594-56-8)

Guidance literature:

With [2,2]bipyridinyl; manganese; (1,2-dimethoxyethane)dichloronickel(II); In N,N-dimethyl-formamide; at 25 ℃; for 20h; chemoselective reaction;

DOI:10.1021/acscatal.0c03428

Reference yield: 99.0%

5,5'-dimethyl-2,2'-dinitro-1,1'-biphenyl (114324-70-8) → 5,5′-dimethyl-[1,1′-biphenyl]-2,2′-diamine (59594-56-8)

Guidance literature:

With palladium on activated charcoal; ammonium formate; In water; isopropyl alcohol; at 20 ℃; for 0.25h;

DOI:10.1055/s-0039-1690759

Reference yield: 82.0%

2-chloro-4-methyl-benzenamine (615-65-6) → 5,5′-dimethyl-[1,1′-biphenyl]-2,2′-diamine (59594-56-8)

Guidance literature:

With [2,2]bipyridinyl; manganese; (1,2-dimethoxyethane)dichloronickel(II); In N,N-dimethyl-formamide; at 25 ℃; for 48h; chemoselective reaction;

DOI:10.1021/acscatal.0c03428

upstream raw materials:

5,5'-dimethyl-2,2'-dinitro-1,1'-biphenyl

2-bromo-p-toluidine

5-methyl-2-nitroaniline

3-bromo-4-nitrotoluene

Downstream raw materials:

3,6-Dimethyl-9H-carbazole