p-(Hexafluoro-2-hydroxypropyl)styrene

Base Information

• Chemical Name: p-(Hexafluoro-2-hydroxypropyl)styrene
• CAS No.: 2386-82-5
• Molecular Formula: C11H8F6O
• Molecular Weight: 270.174
• Hs Code.: 2933499090
• Mol file: 2386-82-5.mol

Synonyms:4-(2,2,2-Trifluoro-1-hydroxy-1-trifluoromethylethyl)styrene;alpha,alpha-Bis(trifluoromethyl)-4-vinylbenzyl alcohol;p-(Hexafluoro-2-hydroxypropyl)styrene

Chemical Property of p-(Hexafluoro-2-hydroxypropyl)styrene

Chemical Property:

• Boiling Point: 74～75℃/3mm
• PKA: 9.24±0.15(Predicted)
• PSA: 20.23000
• Density: 1.379±0.06 g/cm3(Predicted)
• LogP: 3.64180

Purity/Quality:

98%min ^*data from raw suppliers

1,1,1,3,3,3-Hexafluoro-2-(4-vinylphenyl)propan-2-ol 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of p-(Hexafluoro-2-hydroxypropyl)styrene

There total 8 articles about p-(Hexafluoro-2-hydroxypropyl)styrene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

C11H6F6O (639477-50-2) → 1,1,1,3,3,3-hexafluoro-2-(4-vinylphenyl)-2-propanol (2386-82-5)

Guidance literature:

With hydrogen; triphenylphosphine; Lindlar's catalyst; In methanol; at 20 ℃; Product distribution / selectivity;

Reference yield: 65.0%

2-(4-bromophenyl)-1,1,1,3,3,3-hexafluoro-2-propanol (2402-72-4) + vinyl magnesium bromide (1826-67-1) → 1,1,1,3,3,3-hexafluoro-2-(4-vinylphenyl)-2-propanol (2386-82-5)

Guidance literature:

bis(triphenylphosphine)nickel(II) chloride; In tetrahydrofuran; at 0 - 25 ℃; Product distribution / selectivity;

Reference yield: 61.0%

isopropyl vinylborate (92673-05-7) + 2-(4-bromophenyl)-1,1,1,3,3,3-hexafluoro-2-propanol (2402-72-4) → 1,1,1,3,3,3-hexafluoro-2-(4-vinylphenyl)-2-propanol (2386-82-5)

Guidance literature:

With barium dihydroxide; palladium diacetate; In tetrahydrofuran; hexane; water; Product distribution / selectivity; Heating / reflux;

upstream raw materials:

2-(4-bromophenyl)-1,1,1,3,3,3-hexafluoro-2-propanol

tri-n-butyl(vinyl)tin

ethenyltrimethylsilane

ethene

Refernces