2-chloro-1-phenyl-1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid

Base Information

Chemical Name:2-chloro-1-phenyl-1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid
CAS No.:1175015-13-0
Molecular Formula:C₁₄H₉ClN₂O₂
Molecular Weight:272.691
Hs Code.:
Mol file:1175015-13-0.mol

Synonyms:2-chloro-1-phenyl-1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid

Suppliers and Price of 2-chloro-1-phenyl-1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 2-chloro-1-phenyl-1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid

Chemical Property:

Purity/Quality:: 98%min ^*data from raw suppliers

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Technology Process of 2-chloro-1-phenyl-1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid

There total 4 articles about 2-chloro-1-phenyl-1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 847801-39-2
2-chloro-1-phenyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde

: 1175015-13-0
2-chloro-1-phenyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid

Guidance literature:: With sodium chlorite; sodium dihydrogenphosphate; In tert-butyl alcohol; at 20 ℃;
DOI:10.1016/j.bmcl.2011.06.112

Reference yield:

: 1-phenyl-1H-pyrrolo[2,3-b]pyridine

: 1175015-13-0
2-chloro-1-phenyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: bromine / water; tert-butyl alcohol / 20 °C

1.2: 20 °C

2.1: sodium dihydrogenphosphate; sodium chlorite / tert-butyl alcohol / 20 °C

With sodium chlorite; sodium dihydrogenphosphate; bromine; In water; tert-butyl alcohol; 1.1: Vilsmeier-Haack formylation;
DOI:10.1016/j.bmcl.2011.06.112

Reference yield:

: 591-50-4
iodobenzene

: 1175015-13-0
2-chloro-1-phenyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: copper(l) iodide; potassium phosphate; (S,S)-1,2-diaminocyclohexane / 1,4-dioxane / 110 °C

2.1: bromine / water; tert-butyl alcohol / 20 °C

2.2: 20 °C

3.1: sodium dihydrogenphosphate; sodium chlorite / tert-butyl alcohol / 20 °C

With sodium chlorite; potassium phosphate; sodium dihydrogenphosphate; copper(l) iodide; (S,S)-1,2-diaminocyclohexane; bromine; In 1,4-dioxane; water; tert-butyl alcohol; 2.1: Vilsmeier-Haack formylation;
DOI:10.1016/j.bmcl.2011.06.112