Olopatadine Methanol

Base Information

• Chemical Name: Olopatadine Methanol
• CAS No.: 113835-76-0
• Molecular Formula: C21H25NO2
• Molecular Weight: 323.4287
• Mol file: 113835-76-0.mol

Synonyms:Olopatadine Methanol;(11Z)-11-[3-(DiMethylaMino)propylidene]-6,11-dihydro-dibenz[b,e]oxepin-2-ethanol

Chemical Property of Olopatadine Methanol

Chemical Property:

• Boiling Point: 490.7±45.0 °C(Predicted)
• PKA: 14.86±0.10(Predicted)
• PSA: 32.70000
• Density: 1.158±0.06 g/cm3(Predicted)
• LogP: 3.49720

Purity/Quality:

OlopatadineMethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Olopatadine (O575000) derivative, with antiallergic activity.

Technology Process of Olopatadine Methanol

There total 1 articles about Olopatadine Methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 11.0%

olopatadine (113806-05-6) → (Z)-11-<3-(dimethylamino)propylidene>-2-(2-hydroxyethyl)-6,11-dihydrodibenzoxepin (113835-76-0)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 4h; Ambient temperature;

DOI:10.1021/jm00089a020

upstream raw materials:

olopatadine