C10-H13-I-N2-O4

Base Information

Chemical Name:C10-H13-I-N2-O4
CAS No.:83967-03-7
Molecular Formula:C10H13 I N2 O4
Molecular Weight:352.129
Hs Code.:
NSC Number:324060
Mol file:83967-03-7.mol

Synonyms:C-IDU;carbocyclic 2'-deoxy-5-iodouridine;carbocyclic 5-iodo-2'-deoxyuridine;carbocyclic 5-iodo-2'-deoxyuridine, (1R-1alpha,3beta,4alpha)-isomer;carbocyclic 5-iodo-2'-deoxyuridine, (1S-1alpha,3alpha,4beta)-isomer

Suppliers and Price of C10-H13-I-N2-O4

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of C10-H13-I-N2-O4

Chemical Property:

PSA：95.32000
Density:2.01g/cm³
LogP:-0.55450
XLogP3:-0.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:351.99200
Heavy Atom Count:17
Complexity:385

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(CC(C1CO)O)N2C=C(C(=O)NC2=O)I

Technology Process of C10-H13-I-N2-O4

There total 6 articles about C10-H13-I-N2-O4 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 62102-28-7,92007-59-5,99295-53-1,103302-19-8,103302-20-1,114129-20-3,120963-43-1,120963-44-2
(+/-)-1-<(1β,3β,4β)-3-hydroxy-4-(hydroxymethyl)cyclopentyl>-(1H,3H)-pyrimidine-2,4-dione

: 83967-03-7,87421-98-5,114179-59-8,120963-45-3,127181-01-5
1-((1S,3S,4S)-3-Hydroxy-4-hydroxymethyl-cyclopentyl)-5-iodo-1H-pyrimidine-2,4-dione

Guidance literature:: With iodine; nitric acid; In 1,4-dioxane; at 100 ℃; for 1h;
DOI:10.1039/c39900001547

Reference yield: 76.0%

: 62102-28-7
(+/-)-1-<(1β,3α,4β)-3-hydroxy-4-(hydroxymethyl)cyclopentyl>-2,4(1H,3H)-pyrimidinedione

: 83967-03-7
C-IDU

Guidance literature:: With iodine; nitric acid; In chloroform; for 2h; Heating;
DOI:10.1021/jm00356a008

Reference yield:

: 59967-83-8
(+/-)-1-<(1β,2α,3α,4β)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl>-2,4-(1H,3H)-pyrimidinedione

: 83967-03-7
C-IDU

Guidance literature:: Multi-step reaction with 5 steps

1: 80 percent / diphenyl carbonate, sodium bicarbonate / hexamethylphosphoric acid triamide / 0.5 h / 150 °C

2: dimethylformamide; ethyl acetate / 1 h / Heating

3: tributyltin hydride, azobis(isobutyronitrile) / tetrahydrofuran / 0.75 h / Heating

4: sodium methoxide / methanol / Ambient temperature

5: iodine, 0.75 N aq. nitric acid / dioxane / 1 h / 100 °C

With bis(phenyl) carbonate; 2,2'-azobis(isobutyronitrile); iodine; nitric acid; tri-n-butyl-tin hydride; sodium methylate; sodium hydrogencarbonate; In tetrahydrofuran; 1,4-dioxane; methanol; N,N,N,N,N,N-hexamethylphosphoric triamide; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/jm50001a003