6-METHOXYCARBONYL-O-2,2'-ANHYDRO-BETA-D-ARABINOFURANOSYL URACIL

Base Information

• Chemical Name: 6-METHOXYCARBONYL-O-2,2'-ANHYDRO-BETA-D-ARABINOFURANOSYL URACIL
• CAS No.: 36963-58-3
• Molecular Formula: C₁₁H₁₂N₂O₇
• Molecular Weight: 284.225
• Mol file: 36963-58-3.mol

Synonyms:6-METHOXYCARBONYL-O-2,2'-ANHYDRO-BETA-D-ARABINOFURANOSYL URACIL;2,2'-Anhydro-6-methoxycarbonyl-b-D-arabinofuranosyluracil

Chemical Property of 6-METHOXYCARBONYL-O-2,2'-ANHYDRO-BETA-D-ARABINOFURANOSYL URACIL

Chemical Property:

• Melting Point: 241 - 242 °C
• PSA: 120.11000
• LogP: -1.95850

Purity/Quality:

97% ^*data from raw suppliers

2,2'-ANHYDRO-6-METHOXYCARBONYL-BETA-D-ARABINOFURANOSYL URACIL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-METHOXYCARBONYL-O-2,2'-ANHYDRO-BETA-D-ARABINOFURANOSYL URACIL

There total 3 articles about 6-METHOXYCARBONYL-O-2,2'-ANHYDRO-BETA-D-ARABINOFURANOSYL URACIL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

D-arabinofuranose (532-20-7,613-83-2,7261-25-8,7687-39-0,13221-22-2,14795-83-6,15761-67-8,20074-49-1,25545-03-3,25545-04-4,32445-75-3,34436-17-4,36441-93-7,36468-53-8,37110-85-3,37388-49-1,38029-69-5,40461-77-6,40461-89-0,41546-19-4,41546-20-7,41546-21-8,41546-26-3,41546-29-6,41546-30-9,41546-31-0,126872-16-0,131064-98-7) → (3aS)-3c-hydroxy-2t-hydroxymethyl-6-oxo-(3ar,9ac)-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidine-8-carboxylic acid methyl ester (36963-58-3)

Guidance literature:

Multi-step reaction with 2 steps

1: NH₃ / methanol

2: ethanol

With ammonia; In methanol; ethanol;

DOI:10.1021/jo00943a040

Reference yield:

dimethyl acetylenedicarboxylate (762-42-5) + 2-amino-β-D-arabinofurano[1',2':4,5]-oxazoline (27963-98-0) → (3aS)-3c-hydroxy-2t-hydroxymethyl-6-oxo-(3ar,9ac)-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidine-8-carboxylic acid methyl ester (36963-58-3)

Guidance literature:

In ethanol;

DOI:10.1021/jo00943a040

Reference yield:

2-amino-β-L-arabinofurano[1',2':4,5]oxazoline (35939-60-7) + dimethyl acetylenedicarboxylate (762-42-5) → 6-Methoxycarbonyl-O(2,2')-anhydro-L-uridin (L-III) (36959-85-0,36963-58-3)

Guidance literature:

In ethanol; Heating;

DOI:10.1135/cccc19750738

upstream raw materials:

dimethyl acetylenedicarboxylate

2-amino-β-D-arabinofurano[1',2':4,5]-oxazoline

D-arabinofuranose

2-amino-β-L-arabinofurano[1',2':4,5]oxazoline

Downstream raw materials:

(3aR)-3c-benzoyloxy-2t-benzoyloxymethyl-6-oxo-(3ar,9ac)-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidine-8-carboxylic acid methyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 36963-58-3 6-METHOXYCARBONYL-O-2,2'-ANHYDRO-BETA-D-ARABINOFURANOSYL URACIL

Send

Send

Metric Ton KG G Pound L ML

Send

Send