Methyl 3-(4-fluorophenyl)propanoate

Base Information

• Chemical Name: Methyl 3-(4-fluorophenyl)propanoate
• CAS No.: 2928-14-5
• Molecular Formula: C10H11FO2
• Molecular Weight: 182.195
• Hs Code.: 2916399090
• Mol file: 2928-14-5.mol

Synonyms:Methyl 3-(4-fluorophenyl)propanoate;Benzenepropanoic acid, 4-fluoro-, Methyl ester

Chemical Property of Methyl 3-(4-fluorophenyl)propanoate

Chemical Property:

• PSA: 26.30000
• LogP: 1.93130
• Storage Temp.: Room temperature.

Purity/Quality:

99% ^*data from raw suppliers

Methyl3-(4-fluorophenyl)propanoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl 3-(4-fluorophenyl)propanoate

There total 15 articles about Methyl 3-(4-fluorophenyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

methyl (2E)-3-(4-fluorophenyl)-2-propenoate (96426-60-7,100891-10-9) → 3-(4-Fluorophenyl)propionic acid,methyl ester (2928-14-5)

Guidance literature:

With palladium on activated charcoal; hydrogen; In methanol; dichloromethane; at 20 ℃; for 4h;

DOI:10.1021/jacs.0c01330

Reference yield: 92.0%

→ 3-(4-Fluorophenyl)propionic acid,methyl ester (2928-14-5)

Guidance literature:

Reference yield: 90.0%

methyl p-fluorocinnamate (100891-10-9,96426-60-7) → 3-(4-Fluorophenyl)propionic acid,methyl ester (2928-14-5)

Guidance literature:

With hydrazine hydrate; In acetonitrile; at 20 ℃; for 24h; Irradiation;

DOI:10.1002/ejoc.201403021

upstream raw materials:

diazomethane

3-(4-fluorophenyl)propanoic acid

diazomethyl-trimethyl-silane

methyl (2E)-3-(4-fluorophenyl)-2-propenoate

Downstream raw materials:

[4-(4-fluoro-phenyl)-2-oxo-butyl]-phosphonic acid dimethyl ester

methyl 3-(4-fluoro-3-iodophenyl)propanoate

methyl 3-[4-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanoate

6-fluoroindan-1-one