Propyltrityl sulfide

Base Information

• Chemical Name: Propyltrityl sulfide
• CAS No.: 24523-63-5
• Molecular Formula: C₂₂H₂₂S
• Molecular Weight: 318.48
• Mol file: 24523-63-5.mol

Synonyms:Propyltrityl sulfide

Chemical Property of Propyltrityl sulfide

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Propyltrityl sulfide

There total 6 articles about Propyltrityl sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1-thiopropane (107-03-9) + trityl chloride (76-83-5) → S-trityl-3-thiopropanol (24523-63-5)

Guidance literature:

In neat (no solvent); at 50 ℃; for 12h; Schlenk technique; Inert atmosphere;

DOI:10.1002/chem.201902049

Reference yield:

triphenylmethyl alcohol (76-84-6) + 1-thiopropane (107-03-9) → S-trityl-3-thiopropanol (24523-63-5)

Guidance literature:

With 6C₄₁H₃₀N₄O₄*4Fe⁽²⁺⁾*8C₂F₆NO₄S₂^(1-); In [D₃]acetonitrile; at 80 ℃; for 8h; Reagent/catalyst; Temperature;

DOI:10.1002/chem.201902049

Reference yield:

1-thiopropane (107-03-9) + Triphenylmethylethylether (968-39-8) → S-trityl-3-thiopropanol (24523-63-5)

Guidance literature:

With 6C₄₁H₃₀N₄O₄*4Fe⁽²⁺⁾*8C₂F₆NO₄S₂^(1-); In [D₃]acetonitrile; at 80 ℃; Temperature; Reagent/catalyst;

DOI:10.1002/chem.201902049

upstream raw materials:

1-thiopropane

triphenylmethyl alcohol

Triphenylmethylethylether

trityl chloride

Downstream raw materials:

3'-O-acetylthymidine-5'-O-(S-trityl-3-thiopropyl)(2-cyanoethyl)phosphite

Acetic acid (2R,3S,5R)-2-[methoxy-(3-tritylsulfanyl-propoxy)-phosphoryloxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester

3'-O-acetylthymidine-5'-O-(S-trityl-3-thiopropyl)methoxyphosphite

5'-O-(S-trityl-3-thiopropyl)methoxyphosphorylthimidine

Refernces

• 1、 Ngai, Courtney,Bogie, Paul M.,Holloway, Lauren R.,Dietz, Phillip C.,Mueller, Leonard J.,Hooley, Richard J.. "Cofactor-Mediated Nucleophilic Substitution Catalyzed by a Self-Assembled Holoenzyme Mimic". . p. 12000 - 12008. Retrieved 2019.