4-(2-AMinoethyl)benzenesulfonic acid hydrochloride

Base Information

• Chemical Name: 4-(2-AMinoethyl)benzenesulfonic acid hydrochloride
• CAS No.: 1245700-93-9
• Molecular Formula: C8H12ClNO3S
• Molecular Weight: 237.707
• Hs Code.: 2921199090
• Mol file: 1245700-93-9.mol

Synonyms:4-(2-AMinoethyl)benzenesulfonic acid hydrochloride;4-(2-AMinoethyl)benzenesulfonic acid hydrochloric salt

Chemical Property of 4-(2-AMinoethyl)benzenesulfonic acid hydrochloride

Chemical Property:

• Melting Point: >320 °C(Solv: methanol (67-56-1))
• PSA: 88.77000
• LogP: 3.01760
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

4-(2-Aminoethyl)benzenesulfonicacidhydrochloricsalt 97% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(2-AMinoethyl)benzenesulfonic acid hydrochloride

There total 1 articles about 4-(2-AMinoethyl)benzenesulfonic acid hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

4-(2-aminoethyl)benzenesulfonamide (35303-76-5) → 4-(2-aminoethyl)benzenesulfonic acid hydrochloric salt (1245700-93-9)

Guidance literature:

With hydrogenchloride; sodium nitrite; In tetrahydrofuran; water; at 40 ℃; for 24h;

DOI:10.1016/j.bmc.2010.05.072

Reference yield: 40.0%

6-bromomethyl-pteridine-2,4-diamine (59368-16-0) + 4-(2-aminoethyl)benzenesulfonic acid hydrochloric salt (1245700-93-9) → 4-(2-((2,4-diaminopteridin-6-yl)methylamino)ethyl)benzenesulfonic acid (1245700-89-3)

Guidance literature:

4-(2-aminoethyl)benzenesulfonic acid hydrochloric salt; With sodium hydride; In N,N-dimethyl-formamide; paraffin oil; for 0.666667h; Inert atmosphere;

6-bromomethyl-pteridine-2,4-diamine; With calcium carbonate; In N,N-dimethyl-formamide; paraffin oil; at 20 ℃; for 168h; Inert atmosphere; Darkness;

DOI:10.1016/j.bmc.2010.05.072

Reference yield: 32.0%

4-(2-aminoethyl)benzenesulfonic acid hydrochloric salt (1245700-93-9) + 4-(N-tert-butoxycarbonyl)aminobenzoic acid (66493-39-8) → 4-(2-(4-(tert-butoxycarbonylamino)benzamido)ethyl)benzenesulfonic acid (1245700-95-1)

Guidance literature:

4-(N-tert-butoxycarbonyl)aminobenzoic acid; With 4-methyl-morpholine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; In N,N-dimethyl-formamide; for 0.833333h; Inert atmosphere;

4-(2-aminoethyl)benzenesulfonic acid hydrochloric salt; In N,N-dimethyl-formamide; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1016/j.bmc.2010.05.072

upstream raw materials:

4-(2-aminoethyl)benzenesulfonamide

Downstream raw materials:

4-(2-((2,4-diaminopteridin-6-yl)methylamino)ethyl)benzenesulfonic acid

4-(2-(4-(tert-butoxycarbonylamino)benzamido)ethyl)benzenesulfonic acid

Refernces