[4-(4-Fluorophenyl)oxan-4-yl]methanamine

Base Information

Chemical Name:[4-(4-Fluorophenyl)oxan-4-yl]methanamine
CAS No.:889939-79-1
Molecular Formula:C12H16FNO
Molecular Weight:209.264
Hs Code.:2932999099
European Community (EC) Number:846-892-2
DSSTox Substance ID:DTXSID20424426
Wikidata:Q82237000
ChEMBL ID:CHEMBL4548435
Mol file:889939-79-1.mol

Synonyms:889939-79-1;[4-(4-fluorophenyl)oxan-4-yl]methanamine;C-[4-(4-Fluoro-phenyl)-tetrahydro-pyran-4-yl]-methylamine;(4-(4-fluorophenyl)tetrahydro-2H-pyran-4-yl)methanamine;4-(4-Fluorophenyl)oxane-4-methanamine;F2189-0456;SCHEMBL2701757;CHEMBL4548435;DTXSID20424426;AKOS000112601;AB43541;FT-0677966;1-[4-(4-Fluorophenyl)oxan-4-yl]methanamine;EN300-54048;VU0408795-2;C78543;4-(4-Fluorophenyl)-tetrahydropyran-4-yl methylamine;c-[4-(4-fluorophenyl)tetrahydropyran-4-yl]methylamine;Z361884282;C-[4-(4-FLUOROPHENYL)-TETRAHYDROPYRAN-4-YL]-METHYLAMINE

Suppliers and Price of [4-(4-Fluorophenyl)oxan-4-yl]methanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
[4-(4-fluorophenyl)oxan-4-yl]methanamine
50mg
$ 65.00

Crysdot
(4-(4-Fluorophenyl)tetrahydro-2H-pyran-4-yl)methanamine 95+%
5g
$ 874.00

Chemenu
C-[4-(4-Fluoro-phenyl)-tetrahydro-pyran-4-yl]-methylamine 95%
5g
$ 825.00

American Custom Chemicals Corporation
[4-(4-FLUOROPHENYL)OXAN-4-YL]METHANAMINE 95.00%
5G
$ 1548.26

American Custom Chemicals Corporation
[4-(4-FLUOROPHENYL)OXAN-4-YL]METHANAMINE 95.00%
2.5G
$ 1227.82

Alichem
(4-(4-Fluorophenyl)tetrahydro-2H-pyran-4-yl)methanamine
5g
$ 908.46

AK Scientific
C-[4-(4-Fluoro-phenyl)-tetrahydro-pyran-4-yl]-methylamine
1g
$ 465.00

Acrotein
4-(4-Fluorophenyl)oxane-4-methanamine 97%
0.25g
$ 146.67

Total 10 raw suppliers

Chemical Property of [4-(4-Fluorophenyl)oxan-4-yl]methanamine

Chemical Property:

Vapor Pressure:0.000978mmHg at 25°C
Boiling Point:302.6°C at 760 mmHg
Flash Point:136.8°C
PSA：35.25000
Density:1.106g/cm³
LogP:2.53290
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:209.121592296
Heavy Atom Count:15
Complexity:196

Purity/Quality:

97% ^*data from raw suppliers

[4-(4-fluorophenyl)oxan-4-yl]methanamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCC1(CN)C2=CC=C(C=C2)F

Technology Process of [4-(4-Fluorophenyl)oxan-4-yl]methanamine

There total 2 articles about [4-(4-Fluorophenyl)oxan-4-yl]methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 473706-10-4
4-(4-fluorophenyl)tetrahydro-2H-pyran-4-carbonitrile

: 889939-79-1
C₁₂H₁₆FNO

Guidance literature:: With ammonium hydroxide; hydrogen; In ethanol; at 20 ℃; for 23h;
DOI:10.1016/j.bmc.2011.07.030

Reference yield:

: 459-22-3
4-fluorophenylacetonitrile

: 889939-79-1
C₁₂H₁₆FNO

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 3 h / 20 °C / Cooling with ice

2: ammonium hydroxide; hydrogen / ethanol / 23 h / 20 °C

With ammonium hydroxide; hydrogen; sodium hydride; In ethanol; N,N-dimethyl-formamide; mineral oil;
DOI:10.1016/j.bmc.2011.07.030

Reference yield:

: 889939-79-1
C₁₂H₁₆FNO

: C₁₈H₂₅FN₂O₂*ClH

Guidance literature:: Multi-step reaction with 2 steps

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 26 h / 20 °C

2: hydrogenchloride / ethyl acetate / 18 h / 20 °C / Cooling with ice

With hydrogenchloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2011.07.030