N-Methyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide

Base Information

Chemical Name:N-Methyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide
CAS No.:1256359-34-8
Molecular Formula:C15H22BNO3
Molecular Weight:275.15108
Hs Code.:2934999090
DSSTox Substance ID:DTXSID10682275
Wikidata:Q82606589
Mol file:1256359-34-8.mol

Synonyms:1256359-34-8;N-Methyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide;4-(N-Methylaminocarbonyl)methylphenylboronic acid, pinacol ester;N-methyl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetamide;DTXSID10682275;JZQKSRMOFRSRHN-UHFFFAOYSA-N;MFCD16660303;AKOS022184141;AT26673;BS-26510;CS-0176521;EN300-6482249;Z2050054397;N-METHYL-2-[4-(TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL]ACETAMIDE

Suppliers and Price of N-Methyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(N-Methylaminocarbonyl)methylphenylboronicacid,pinacolester
50mg
$ 45.00

Crysdot
N-Methyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide 95+%
10g
$ 1065.00

Crysdot
N-Methyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide 95+%
5g
$ 664.00

Chemenu
N-Methyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide 98%
5g
$ 622.00

Chemenu
N-Methyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide 98%
1g
$ 186.00

Chemenu
N-Methyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide 98%
10g
$ 995.00

AK Scientific
4-(N-Methylaminocarbonyl)methylphenylboronicacidpinacolester
5g
$ 851.00

Total 10 raw suppliers

Chemical Property of N-Methyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide

Chemical Property:

PSA：51.05000
LogP:2.11460
Storage Temp.:Room temperature.
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:275.1692737
Heavy Atom Count:20
Complexity:346

Purity/Quality:

95% ^*data from raw suppliers

4-(N-Methylaminocarbonyl)methylphenylboronicacid,pinacolester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2=CC=C(C=C2)CC(=O)NC

Technology Process of N-Methyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide

There total 3 articles about N-Methyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 7713-76-0
2-(4-bromophenyl)-N-methylethanamide

: 73183-34-3
bis(pinacol)diborane

: 1256359-34-8
2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-N-methylethanamide

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; potassium acetate; In 1,4-dioxane; at 100 ℃; Inert atmosphere;
DOI:10.1016/j.bmc.2012.11.054

Reference yield:

: 1878-68-8
2-(4-bromophenyl)-acetic acid

: 1256359-34-8
2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-N-methylethanamide

Guidance literature:: Multi-step reaction with 2 steps

1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine / dichloromethane; methanol / 23 h / 20 °C

2: potassium acetate; bis-triphenylphosphine-palladium(II) chloride / 1,4-dioxane / 100 °C / Inert atmosphere

With bis-triphenylphosphine-palladium(II) chloride; potassium acetate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; methanol; dichloromethane;
DOI:10.1016/j.bmc.2012.11.054