1-Chloro-4-[(2-chloroethyl)thio]benzene

Base Information

• Chemical Name: 1-Chloro-4-[(2-chloroethyl)thio]benzene
• CAS No.: 14366-73-5
• Molecular Formula: C8H8 Cl2 S
• Molecular Weight: 207.124
• Hs Code.: 2930909090
• European Community (EC) Number: 238-338-8
• NSC Number: 11120
• UNII: R3R7VDC58P
• DSSTox Substance ID: DTXSID30162488
• Nikkaji Number: J216.989D
• Wikidata: Q83031168
• Mol file: 14366-73-5.mol

Synonyms:14366-73-5;1-chloro-4-[(2-chloroethyl)thio]benzene;1-chloro-4-[(2-chloroethyl)sulfanyl]benzene;1-chloro-4-(2-chloroethylsulfanyl)benzene;2-chloroethyl 4-chlorophenyl sulfide;1-Chloro-4-((2-chloroethyl)thio)benzene;C8H8Cl2S;R3R7VDC58P;EINECS 238-338-8;NSC-11120;Benzene, 1-chloro-4-((2-chloroethyl)thio)-;NSC11120;UNII-R3R7VDC58P;SCHEMBL1274257;DTXSID30162488;MFCD00018965;NSC 11120;AKOS001116903;EN300-09143;Z55993025

Chemical Property of 1-Chloro-4-[(2-chloroethyl)thio]benzene

Chemical Property:

• Vapor Pressure: 0.00616mmHg at 25°C
• Boiling Point: 281.2°Cat760mmHg
• Flash Point: 120.3°C
• PSA: 25.30000
• Density: 1.29g/cm³
• LogP: 3.67090
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 205.9723768
• Heavy Atom Count: 11
• Complexity: 100

Purity/Quality:

99% ^*data from raw suppliers

1-chloro-4-[(2-chloroethyl)sulfanyl]benzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC(=CC=C1SCCCl)Cl

Technology Process of 1-Chloro-4-[(2-chloroethyl)thio]benzene

There total 9 articles about 1-Chloro-4-[(2-chloroethyl)thio]benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-[(4-Chlorophenyl)thio]ethanol (13457-98-2) → 2-chloroethyl 4-chlorophenyl sulfide (14366-73-5)

Guidance literature:

With thionyl chloride; In chloroform; for 1h;

DOI:10.1039/b713668b

Reference yield: 85.7%

(4-chlorophenylthio)trimethylsilane (30718-19-5) + 1-Bromo-2-chloroethane (107-04-0) → 2-chloroethyl 4-chlorophenyl sulfide (14366-73-5)

Guidance literature:

In N,N,N,N,N,N-hexamethylphosphoric triamide;

Reference yield: 35.0%

2-[(4-Chlorophenyl)thio]ethanol (13457-98-2) → 2-chloroethyl 4-chlorophenyl sulfide (14366-73-5) + (2-chloro-ethyl)-(2,4-dichloro-phenyl)-sulfide (876493-12-8)

Guidance literature:

aluminium trichloride; nitromethane; In carbon disulfide; for 40h; Ambient temperature;

upstream raw materials:

2-[(4-Chlorophenyl)thio]ethanol

ethene

4-chloro-benzenesulfenyl chloride

1-Chloro-4-iodobenzene

Downstream raw materials:

p-chlorophenyl ethyl sulfide

2-chloro-1-[(4-chlorophenyl)sulfonyl]ethane

1,2-bis((4-chlorophenyl)thio)ethane

ethene

Refernces

• 1、 Angamuthu, Raja,Kooijman, Huub,Lutz, Martin,Spek, Anthony L.,Bouwman, Elisabeth. "Hexanuclear [Ni6L12] metallacrown framework consisting of NiS4 square-planar and NiS5 square-pyramidal building blocks". . p. 4641 - 4643. Retrieved 2008/03/13.
• 2、 Bauld, Nathan L.,Aplin, J. Todd,Yueh, Wang,Endo, Stephanie,Loving, Angie. "Convenient criterion for the distinction between electrophilic and electron transfer reactions of electron-rich alkenes". . p. 15 - 24. Retrieved 2007/10/03.