13457-98-2

Basic information

• Product Name: 4-CHLOROPHENYL 2-HYDROXYETHYL SULPHIDE
• Synonyms: 4-CHLOROPHENYL-2-HYDROXYETHYL SULFIDE;4-CHLOROPHENYL 2-HYDROXYETHYL SULPHIDE;BUTTPARK 146\04-74;SALOR-INT L308781-1EA;2-(p-chlorophenylthio)ethanol;Ethanol, 2-((4-chlorophenyl)thio)-;4-CHLOROPHENYL 2-HYDROXYETHYL SULPHIDE 98%;P-CHLOROPHENYL 2-HYDROXYETHYL SULFIDE, 99%
• CAS NO: 13457-98-2
• Molecular Formula: C₈H₉ClOS
• Molecular Weight: 188.67
• EINECS: 236-657-7
• Mol File: 13457-98-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 304.8 °C at 760 mmHg
• Flash Point: 138.1 °C
• Appearance: /
• Density: 1.29 g/cm³
• Vapor Pressure: 0.000375mmHg at 25°C
• Refractive Index: 1.608
• Storage Temp.: 2-8°C
• PKA: 14.32±0.10(Predicted)
• CAS DataBase Reference: 4-CHLOROPHENYL 2-HYDROXYETHYL SULPHIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLOROPHENYL 2-HYDROXYETHYL SULPHIDE(13457-98-2)
• EPA Substance Registry System: 4-CHLOROPHENYL 2-HYDROXYETHYL SULPHIDE(13457-98-2)

Safety Data

• Hazard Codes: Xi
• Statements: R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
• Safety Statements: S36/37:Wear suitable protective clothing and gloves.
• HazardClass: IRRITANT
• Hazardous Substances Data: 13457-98-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4-Chlorophenyl 2-Hydroxyethyl Sulphide is used as an intermediate in the synthesis of various pharmaceutical compounds for its antibacterial properties, contributing to the development of medications aimed at combating bacterial infections.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Chlorophenyl 2-Hydroxyethyl Sulphide is utilized as an intermediate in the production of agrochemicals, leveraging its antibacterial properties to create products that protect crops and enhance agricultural yields.
Used in Organic Compound Synthesis:
4-Chlorophenyl 2-Hydroxyethyl Sulphide is employed as a key component in the synthesis of a variety of organic compounds, highlighting its versatility in chemical reactions and its importance in creating new chemical entities for various applications.

InChI:InChI=1/C8H9ClOS/c9-7-1-3-8(4-2-7)11-6-5-10/h1-4,10H,5-6H2

Upstream product

• 18803-44-6 sodium p-chlorothiophenolate 
• 107-07-3 2-chloro-ethanol 
• 106-54-7 p-Chlorothiophenol 

Downstream Products

• 107737-92-8 C₈H₉ClO₂S 
• 175137-71-0 C₁₀H₁₁ClO₄S₂ 
• 1111237-98-9 C₁₈H₁₈ClNO₆S 
• 90416-54-9 <4-Chlor-phenyl>-<2-methylsulfonyloxy-aethyl>-sulfon 
• 118695-62-8 <2-(p-chlorophenylsulfonyl)ethoxycarbonyl>leucine methyl ester 
• 118709-90-3 Phenyl-carbamic acid 2-(4-chloro-benzenesulfonyl)-ethyl ester 
• 112723-64-5 2-(p-chlorophenylsulfonyl)ethyl chloroformate 
• 14366-73-5 2-chloroethyl 4-chlorophenyl sulfide 
• 876493-12-8 (2-chloro-ethyl)-(2,4-dichloro-phenyl)-sulfide 
• 35847-95-1 2-[(4-chlorophenyl)sulfonyl]ethanol 
• 16191-84-7 2-chloro-1-[(4-chlorophenyl)sulfonyl]ethane 

Relevant articles and documents

Synthesis and evaluation of sulfonylethyl-containing phosphotriesters of 3′-azido-3′-deoxythymidine as anticancer prodrugs

A series of bis(sulfonylethyl) and mono(sulfonylethyl) phenyl phosphotriesters of zidovudine (3′-azido-3′-deoxythymidine, AZT) were synthesized as potential anticancer prodrugs that liberate AZT monophosphate via nonenzymatic β-elimination mechanism. Stab

Synthesis of a new class of arylsulfonylethylsulfonylmethyloxazolines and thiazolines

A new class of arylsulfonylethylsulfonylmethyl oxazolines and thiazolines were prepared using multistep, one-pot methodologies exploiting lanthanide alkoxides and under microwave irradiation. The microwave method provides an excellent approach in a single step with high yields.

Hexanuclear [Ni6L12] metallacrown framework consisting of NiS4 square-planar and NiS5 square-pyramidal building blocks

The hexanuclear [Ni6L12] (2) wheel-type cluster adopts an unusual structural motif whereby four NiS4 square-planar and two NiS5 square-pyramidal units are conjoined by edge sh? the NiS5 units resemble the Ni centre of the inactive state in the [NiFe] hydrogenase. The Royal Society of Chemistry 2007.