Ethyl 3-methyl-5-[(phenylcarbamoyl)amino]-1,2-thiazole-4-carboxylate

Base Information

Chemical Name:Ethyl 3-methyl-5-[(phenylcarbamoyl)amino]-1,2-thiazole-4-carboxylate
CAS No.:92376-38-0
Molecular Formula:C₁₄H₁₅N₃O₃S
Molecular Weight:305.357
Hs Code.:
DSSTox Substance ID:DTXSID70589377
Wikidata:Q82482712
Mol file:92376-38-0.mol

Synonyms:92376-38-0;DTXSID70589377;Ethyl 3-methyl-5-[(phenylcarbamoyl)amino]-1,2-thiazole-4-carboxylate;DB-083107

Suppliers and Price of Ethyl 3-methyl-5-[(phenylcarbamoyl)amino]-1,2-thiazole-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-METHYL-5-(3-PHENYLUREIDO)-4-ISOTHIAZOLECARBOXYLIC ACID ETHYL ESTER 95.00%
5MG
$ 505.95

Total 4 raw suppliers

Chemical Property of Ethyl 3-methyl-5-[(phenylcarbamoyl)amino]-1,2-thiazole-4-carboxylate

Chemical Property:

Boiling Point:320.2±42.0 °C(Predicted)
PKA:12.42±0.70(Predicted)
PSA：112.05000
Density:1.367±0.06 g/cm3(Predicted)
LogP:3.35880
XLogP3:3.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:305.08341252
Heavy Atom Count:21
Complexity:375

Purity/Quality:

98% ^*data from raw suppliers

3-METHYL-5-(3-PHENYLUREIDO)-4-ISOTHIAZOLECARBOXYLIC ACID ETHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C1=C(SN=C1C)NC(=O)NC2=CC=CC=C2

Technology Process of Ethyl 3-methyl-5-[(phenylcarbamoyl)amino]-1,2-thiazole-4-carboxylate

There total 2 articles about Ethyl 3-methyl-5-[(phenylcarbamoyl)amino]-1,2-thiazole-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 63089-25-8
2-(1-amino-ethylidene)-N-phenoxycarbonyl-3-thio-malonamic acid ethyl ester

: 92376-38-0
3-methyl-5-(3-phenyl-ureido)-isothiazole-4-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: Br₂ / ethyl acetate

2: dimethylformamide

With bromine; In ethyl acetate; N,N-dimethyl-formamide;

Reference yield:

: 626-34-6,7318-00-5,41867-20-3
ethyl aminocrotonate

: 92376-38-0
3-methyl-5-(3-phenyl-ureido)-isothiazole-4-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: (i), (ii) /BRN= 471282/

2: Br₂ / ethyl acetate

3: dimethylformamide

With bromine; In ethyl acetate; N,N-dimethyl-formamide;