Technology Process of Propanedioic acid, (phenylmethyl)-, monoethyl ester, (R)- (9CI)
There total 12 articles about Propanedioic acid, (phenylmethyl)-, monoethyl ester, (R)- (9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium hydroxide;
In
ethanol;
for 5h;
Ambient temperature;
DOI:10.3987/COM-97-S24
- Guidance literature:
-
dibenzylmalonic acid diethyl ester;
With
N1,N1,N12,N12-tetramethyl-7,8-dihydro-6H-dipyrido[1,2-a:2,1'-c][1,4]diazepine-2,12-diamine;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 72h;
Inert atmosphere;
Glovebox;
UV-irradiation;
With
hydrogenchloride;
In
water;
at 0 ℃;
pH=< 3;
chemoselective reaction;
Inert atmosphere;
DOI:10.1021/ja4050168
- Guidance literature:
-
ethanol; diethyl 2-benzylmalonate;
With
potassium hydroxide;
In
water;
at 18 - 25 ℃;
With
hydrogenchloride;
In
water;
DOI:10.1021/acs.orglett.9b02291