(7R,8R,9S,13S,14S,17S)-3-Methoxy-7,13-dimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-ol

Base Information

Chemical Name:(7R,8R,9S,13S,14S,17S)-3-Methoxy-7,13-dimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-ol
CAS No.:15506-01-1
Molecular Formula:C20H28O2
Molecular Weight:300.441
Hs Code.:
DSSTox Substance ID:DTXSID20576954
Mol file:15506-01-1.mol

Synonyms:15506-01-1;(7R,8R,9S,13S,14S,17S)-3-Methoxy-7,13-dimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-ol;SCHEMBL1221330;DTXSID20576954

Suppliers and Price of (7R,8R,9S,13S,14S,17S)-3-Methoxy-7,13-dimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
(7α,17β)-3-Methoxy-7-methyl-estra-1,3,5(10)-trien-17-ol
200 mg
$ 2200.00

Medical Isotopes, Inc.
(7α,17β)-3-Methoxy-7-methyl-estra-1,3,5(10)-trien-17-ol
20 mg
$ 650.00

Total 3 raw suppliers

Chemical Property of (7R,8R,9S,13S,14S,17S)-3-Methoxy-7,13-dimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-ol

Chemical Property:

Melting Point:129-131 °C
Boiling Point:434.7±45.0 °C(Predicted)
PKA:15.07±0.60(Predicted)
PSA：29.46000
Density:1.079±0.06 g/cm3(Predicted)
LogP:4.15820
Solubility.:Dichloromethane, Ethyl Acetate
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:300.208930132
Heavy Atom Count:22
Complexity:422

Purity/Quality:

99% ^*data from raw suppliers

(7α,17β)-3-Methoxy-7-methyl-estra-1,3,5(10)-trien-17-ol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CC2=C(C=CC(=C2)OC)C3C1C4CCC(C4(CC3)C)O
Isomeric SMILES:C[C@@H]1CC2=C(C=CC(=C2)OC)[C@@H]3[C@@H]1[C@@H]4CC[C@@H]([C@]4(CC3)C)O
Uses (7α,17β)-3-Methoxy-7-Methyl-estra-1,3,5(10)-trien-17-ol can be used in the preparation of alkylated estratrienes.

Technology Process of (7R,8R,9S,13S,14S,17S)-3-Methoxy-7,13-dimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-ol

There total 11 articles about (7R,8R,9S,13S,14S,17S)-3-Methoxy-7,13-dimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 199529-04-9
(7S,8R,9S,13S,14S,17S)-3-Methoxy-7,13-dimethyl-17-(tetrahydro-pyran-2-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-cyclopenta[a]phenanthren-6-one

: 15506-01-1
3-methoxy-7α-methylestra-1,3,5(10)-trien-17β-ol

Guidance literature:: With triethylsilane; boron trifluoride diethyl etherate; In dichloromethane; at 0 ℃; for 12h;
DOI:10.1016/S0040-4039(97)10180-0