L-Proline, 4-(benzoylaMino)-, Methyl ester, hydrochloride (1:1), (4R)-

Base Information

Chemical Name:L-Proline, 4-(benzoylaMino)-, Methyl ester, hydrochloride (1:1), (4R)-
CAS No.:943134-38-1
Molecular Formula:C13H17ClN2O3
Molecular Weight:284.743
Hs Code.:
Mol file:943134-38-1.mol

Synonyms:L-Proline, 4-(benzoylaMino)-, Methyl ester, hydrochloride (1:1), (4R)-;L-Proline, 4-(benzoylaMino)-, Methyl ester, hydrochloride (1:1), (4R)-6

Suppliers and Price of L-Proline, 4-(benzoylaMino)-, Methyl ester, hydrochloride (1:1), (4R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
L-Proline,4-(benzoylamino)-,methylester,hydrochloride(1:1),(4R)-
100mg
$ 227.00

AK Scientific
L-Proline,4-(benzoylamino)-,methylester,hydrochloride(1:1),(4R)-
250mg
$ 581.60

AK Scientific
L-Proline,4-(benzoylamino)-,methylester,hydrochloride(1:1),(4R)-
100mg
$ 369.20

Total 5 raw suppliers

Chemical Property of L-Proline, 4-(benzoylaMino)-, Methyl ester, hydrochloride (1:1), (4R)-

Chemical Property:

PSA：67.43000
LogP:1.84160

Purity/Quality:

95-99% ^*data from raw suppliers

L-Proline,4-(benzoylamino)-,methylester,hydrochloride(1:1),(4R)- ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of L-Proline, 4-(benzoylaMino)-, Methyl ester, hydrochloride (1:1), (4R)-

There total 2 articles about L-Proline, 4-(benzoylaMino)-, Methyl ester, hydrochloride (1:1), (4R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 943134-37-0
1-tert-butyl 2-methyl (2S,4R)-4-benzamidopyrrolidine-1,2-dicarboxylate

: 943134-38-1
methyl (2S,4R)-4-benzamidopyrrolidine-2-carboxylate hydrochloride

Guidance literature:: With hydrogenchloride; In diethyl ether; at 20 ℃; for 45.0833h;

Reference yield:

: 1035596-37-2
(2S,4R)-1-benzyl 2-methyl 4-benzamidopyrrolidine-1,2-dicarboxylate

: 943134-38-1
methyl (2S,4R)-4-benzamidopyrrolidine-2-carboxylate hydrochloride

Guidance literature:: (2S,4R)-1-benzyl 2-methyl 4-benzamidopyrrolidine-1,2-dicarboxylate; With cyclohexene; palladium 10% on activated carbon; In methanol; for 7h; Heating / reflux;

With hydrogenchloride; In methanol; diethyl ether; at 20 - 25 ℃; Product distribution / selectivity;

Reference yield: 85.8%

: 4530-20-5
BOC-glycine

: 943134-38-1
methyl (2S,4R)-4-benzamidopyrrolidine-2-carboxylate hydrochloride

: 943134-40-5
methyl (2S,4R)-4-benzamido-1-(2-(tert-butoxycarbonylamino)acetyl)pyrrolidine-2-carboxylate

Guidance literature:: methyl (2S,4R)-4-benzamidopyrrolidine-2-carboxylate hydrochloride; With triethylamine; In dichloromethane; at 15 - 25 ℃; for 0.25h;

BOC-glycine; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 15 - 25 ℃; for 1h; Product distribution / selectivity;